Results 1 to 10 of about 65,430 (260)

Better olfaction was associated with lower healthcare expenditure among physically independent Japanese community-dwelling older adults: the Yanai study [PDF]

open access: yesFrontiers in Aging
ObjectiveWe aimed to determine whether olfaction is associated with healthcare expenditure among physically independent, community-dwelling older adults.MethodsThis cross-sectional study included 162 community-dwelling older adults (mean age 70.2 ± 5.4 ...
Yujiro Kose   +17 more
doaj   +2 more sources

Up the nose of the beholder? Aesthetic perception in olfaction as a decision-making process [PDF]

open access: yes, 2014
Is the sense of smell a source of aesthetic perception? Traditional philosophical aesthetics has centered on vision and audition but eliminated smell for its subjective and inherently affective character.
Bailey Aubrey   +7 more
core   +16 more sources

NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss

open access: yesFrontiers in Cell and Developmental Biology, 2022
The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset   +8 more
doaj   +1 more source

WNT Activation and TGFβ-Smad Inhibition Potentiate Stemness of Mammalian Auditory Neuroprogenitors for High-Throughput Generation of Functional Auditory Neurons In Vitro

open access: yesCells, 2022
Hearing loss affects over 460 million people worldwide and is a major socioeconomic burden. Both genetic and environmental factors (i.e., noise overexposure, ototoxic drug treatment and ageing), promote the irreversible degeneration of cochlear hair ...
Francis Rousset   +6 more
doaj   +1 more source

COVID-19 Smell Impairment and Crosstalk with Hypoxia Physiology

open access: yesLife, 2022
Since its apomorphic appearance in 2019, severe acute respiratory syndrome Coronavirus type 2 (SARS-CoV-2) nowadays circulates as a plesiomorphic human virus in several synapomorphic variants. The respiratory tract is the most important site of infection,
Andrea Mazzatenta   +3 more
doaj   +1 more source

Development and in vivo validation of small interfering RNAs targeting NOX3 to prevent sensorineural hearing loss

open access: yesFrontiers in Neurology, 2022
The reactive oxygen species (ROS)-generating enzyme NOX3 has recently been implicated in the pathophysiology of several acquired forms of sensorineural hearing loss, including cisplatin-, noise- and age-related hearing loss.
German Nacher-Soler   +8 more
doaj   +1 more source

Clinical Implications of Septal Deviation in Lateralized Olfaction [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2016
Objectives Results of butanol threshold tests (BTTs) have shown that birhinal olfaction tends to converge toward monorhinal olfaction of the dominant nostril. However, birhinal olfaction may also be worse than dominant-side monorhinal olfaction. The goal
Yoon-Seok Choi   +6 more
doaj   +1 more source

Second-generation non-hematopoietic erythropoietin-derived peptide for neuroprotection

open access: yesRedox Biology, 2022
Erythropoietin (EPO) is a well-known erythropoietic cytokine having a tissue-protective effect in various tissues against hypoxic stress, including the brain. Thus, its recombinants may function as neuroprotective compounds. However, despite considerable
Bongki Cho   +6 more
doaj   +1 more source

“Emotional Nose”: The Hedonic Character of Olfaction and its Epistemological and Clinical Implications [PDF]

open access: yes, 2020
The olfactory system is the oldest device that most organisms have to perceive their physical and social environment. However, progressing in the evolutionary tree, the importance of the olfactory perception has decreased, and the sight has taken ...
Bochicchio, Vincenzo   +3 more
core   +1 more source

Why human olfaction should not be modeled on theories and tasks of vision

open access: yesFrontiers in Psychology, 2023
In this paper we analyze some key concepts and problems in olfaction and argue that many concepts borrowed from vision are not helpful in elucidating the functions of human olfaction. This is illustrated with several examples.
Per Møller, Egon P. Köster
doaj   +1 more source

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