Results 191 to 200 of about 3,695,100 (289)

The detection dogs test is more sensitive than real-time PCR in screening for SARS-CoV-2. [PDF]

Commun Biol, 2021
Hag-Ali M, AlShamsi AS, Boeijen L, Mahmmod Y, Manzoor R, Rutten H, Mweu MM, El-Tholoth M, AlShamsi AA.   +8 more
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Discrimination of SARS-CoV-2 infected patient samples by detection dogs: A proof of concept study. [PDF]

PLoS One, 2021
Essler JL, Kane SA, Nolan P, Akaho EH, Berna AZ, DeAngelo A, Berk RA, Kaynaroglu P, Plymouth VL, Frank ID, Weiss SR, Odom John AR, Otto CM.   +12 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Calibrating canines-a universal detector calibrant for detection dogs. [PDF]

Front Allergy
Maughan MN, Gadberry JD, Sharpes CE, Buckley PE, Miklos AE, Furton KG, DeGreeff LE, Hall NJ, Greubel RR, Sloan KB.   +9 more
europepmc   +1 more source

A medical detection role for dogs

, 2016
Dr Nicola Rooney (BSc PGCE PhD), Research Fellow and Lecturer in the Animal Welfare and Behaviour Group at the University of Bristol, has headed a team conducting research on working dogs for the past 15 years. She shares her expertise with our readers, examining a range of methods for training dogs to detect odours which are associated with human ...
openaire   +1 more source

Dog Activity Detection and Recognition

This paper presents a comprehensive study on a sensor-based dog activity recognition system aimed at enhancing canine well-being. Utilizing wearable sensors and machine learning algorithms, the research explores methodologies for data collection, annotation, preprocessing, and model training.
openaire   +2 more sources

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Detection Dogs Working in Hot Climates: The Influence on Thermoregulation and Fecal Consistency. [PDF]

Animals (Basel)
Slotta-Bachmayr L, Oyugi A, Mutoro N, Burak M, Wykstra M.   +4 more
europepmc   +1 more source