Results 61 to 70 of about 6,940,219 (310)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Report of the Energy Efficiency Board. 2013.
Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
An algorithm for estimating the detection efficiency of a lightning location system
This article puts forward an algorithm for estimating the detection efficiency (DE) of a lightning location system (LLS). The algorithm can be applied to lightning flash/stroke density correction and LLS performance evaluation.
HaiBo Hu, Ying Wang, Xiya Zhang
doaj +1 more source
Artificially triggered lightning refers to the lightning that is artificially triggered to the ground under appropriate thunderstorm conditions. The location of artificially triggered lightning can be determined; the occurring time can be precisely ...
Zhang Yue +9 more
doaj +1 more source
Efficient detection of quasiperiodicities in strings
A strings \(z\) is quasiperiodic if there is a string \(w\neq z\) such that \(z\) is completely by (possibly overlapping) occurrences of \(w\) in \(z\). In this situation \(w\) is called a quasiperiod of \(z\). If \(z\) is quasiperiodic, then its shortest quasiperiod \(w\) is uniquely determined and is referred to as the quasiperiod of \(z\).
Apostolico, Alberto +1 more
openaire +3 more sources
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The planar “two-dimension isochronous time-of-flight (2DisoTOF)” is a new type of multiple-reflection time-of-flight mass analyzer. It is composed of a series of flat plate electrodes arranged in parallel, boasting advantages such as simple structure ...
Meng-jie DAI +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

