Results 111 to 120 of about 8,972,343 (398)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Statistics of gamma-ray point sources below the Fermi detection limit
, 2011 An analytic relation between the statistics of photons in pixels and the number counts of multi-photon point sources is used to constrain the distribution of gamma-ray point sources below the Fermi detection limit at energies above 1 GeV and at latitudes
Abazajian +32 more
core +1 more source
Approaching the Heisenberg limit with two mode squeezed states [PDF]
, 2002 Two mode squeezed states can be used to achieve Heisenberg limit scaling in interferometry: a phase shift of $\delta \phi \approx 2.76 / $ can be resolved.
Arvind +21 more
core +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A high-sensitivity OH 5-cm line survey in late-type stars
, 2002 We have undertaken a comprehensive search for 5-cm excited OH maser emission from evolved stars representative of various stages of late stellar evolution. Observed sources were selected from known 18-cm OH sources. This survey was conducted with the 100-
Baudry, A. +3 more
core +1 more source
Limit theorems for bifurcating Markov chains. Application to the detection of cellular aging [PDF]
, 2006 We propose a general method to study dependent data in a binary tree, where an individual in one generation gives rise to two different offspring, one of type 0 and one of type 1, in the next generation.
Guyon, Julien
core +1 more source
, 2008 Citation: 'detection limit' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01629 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Strong Quantum Spin Correlations Observed in Atomic Spin Mixing
, 2011 We have observed sub-Poissonian spin correlations generated by collisionally induced spin mixing in a spin-1 Bose-Einstein condensate. We measure a quantum noise reduction of -7 dB (-10 dB corrected for detection noise) below the standard quantum limit ...
Christopher D. Hamley +4 more
core +1 more source
Sensitive detection of methane at 3.3 μm using an integrating sphere and interband cascade laser [PDF]
, 2016 Detection of methane at 3.3μm using a DFB Interband Cascade Laser and gold coated integrating sphere is performed. A 10cm diameter sphere with effective path length of 54.5cm was adapted for use as a gas cell.
Davis, Nicholas M. +3 more
core +1 more source