Results 131 to 140 of about 4,854,135 (253)

"Uniform Measures On Inverse Limit Spaces" [PDF]

open access: yes
Motivated by problems from dynamic economic models, we consider the problem of defining a uniform measure on inverse limit spaces. Let f be a function from a compact metric space X into itself where f is continuous, onto and piecewise one-to-one.
David R. Stockman
core  

Hitting the Detection Limit in cAMP Signaling. [PDF]

open access: yesFunction (Oxf), 2022
Klein F, Machado MR, Pantano S.
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Optofluidic integrated Bragg grating chemical sensor: Utilising a sodium-elective receptor surface to enhance detection

open access: yes
Planar waveguides can be written with a UV-laser into photosensitised silica to produce a wide range of optical devices. Careful modulation of two interfering beams allows Bragg gratings to be directly written into the channel.
Grossel, M.C.   +3 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

X-ray-Induced Pyroelectric Effect in a Perovskite Ferroelectric Drives Low Detection Limit Self-Powered Responses. [PDF]

open access: yesACS Cent Sci, 2023
Ma Y   +9 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Improvement of Tunable Diode Laser Absorption System with a Novel Multipass Cell and Wavelet Transform

open access: yesJournal of Measurement Science and Instrumentation, 2011
Combination of Tunable Diode Laser Absorption Spectroscopy(TDLAS)technique and multipass cell is an attractive approach for ultrahigh sensitive detection of trace gases.Theoretically,based on Beer-Lambert law,the longer optical path length and the larger
Hua XIA   +5 more
doaj  

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