Results 141 to 150 of about 2,444,726 (301)
Zhongguo shipin weisheng zazhiObjectiveTo develop a high-performance liquid chromatography-based method for the determination of L-threonate in magnesium L-threonate products.MethodsThe samples were dissolved in water and separated by C18 reversed-phase chromatography with 0.1 ...
TIAN Hongyun +7 more
doaj +1 more source
Theoretical and experimental study on the detection limit of the micro-ring resonator based ultrasound point detectors. [PDF]
Photoacoustics, 2023 Lee Y +6 more
europepmc +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Toward the Detection Limit of Electrochemistry: Studying Anodic Processes with a Fluorogenic Reporting Reaction. [PDF]
Anal Chem, 2023 Linfield S, Gawinkowski S, Nogala W.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Toward single particle reconstruction without particle picking: Breaking the detection limit
, 2018 Single-particle cryo-electron microscopy (cryo-EM) has recently joined X-ray crystallography and NMR spectroscopy as a high-resolution structural method for biological macromolecules.
Bendory, Tamir +4 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Hitting the Detection Limit in cAMP Signaling. [PDF]
Function (Oxf), 2022 Klein F, Machado MR, Pantano S.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
X-ray-Induced Pyroelectric Effect in a Perovskite Ferroelectric Drives Low Detection Limit Self-Powered Responses. [PDF]
ACS Cent Sci, 2023 Ma Y +9 more
europepmc +1 more source