Results 141 to 150 of about 1,026,341 (311)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Droplet digital polymerase chain reaction for rapid broad-spectrum detection of bloodstream infections

open access: yes, 2019
Contains fulltext : 218675.pdf (Publisher’s version ) (Open Access)The droplet digital polymerase chain reaction (ddPCR) is a novel molecular technique that allows rapid quantification of rare target DNA sequences. Aim of this study was
Heiman F. Wertheim   +28 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Improving detection limit of non-dispersive infrared gas sensor with high precision by matched filtering

open access: yesInternational Journal of Optomechatronics
Non-dispersive infrared (NDIR) gas sensors have the disadvantage of high limit of detection (LOD), and the signal-to-noise ratio (SNR) has a significant impact on LOD.
An Nie   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Quantum Limits of Covert Target Detection

open access: yesPhysical Review Letters
20 pages, 5 ...
Guo Yao Tham, Ranjith Nair, Mile Gu
openaire   +4 more sources

High-performance magnetoelectric sensors based on multi-electrode series connection for weak magnetic field detection

open access: yesJournal of Advanced Dielectrics
This study introduces a high-sensitivity magnetoelectric (ME) sensor featuring a novel multi-electrode, series-connected configuration for ultra-weak magnetic field detection.
Yulong Liu   +9 more
doaj   +1 more source

Limit of detection dataset for PCR assays

open access: yes
Dataset outlining limit of detection for PCR ...
Trianty, Leily   +24 more
core   +1 more source

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