Results 251 to 260 of about 8,972,343 (398)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Extending the detection limit: innovations in infrared quantum dot photodetectors reaching up to 18 μm. [PDF]

Light Sci Appl
Wang CW, Wang QJ.
europepmc   +1 more source

Imputation of Below Detection Limit Missing Data in Chemical Mixture Analysis with Bayesian Group Index Regression. [PDF]

Int J Environ Res Public Health, 2022
Carli M, Ward MH, Metayer C, Wheeler DC.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Single high-sensitivity troponin-I for ruling out acute coronary syndrome: a detection limit approach. [PDF]

Eur Heart J Open
Hickling S, Francis CJ, Chew DP, Mitra B, Hillis GS.   +4 more
europepmc   +1 more source

Ultra-low detection limit chemoresistive NO₂ gas sensor using single transferred MoS₂ flake: an advanced nanofabrication. [PDF]

RSC Adv, 2022
Hong HS, Hoang TV, Hoang TV, Huong NT, Nam NH, Thinh DD, Hue NT, Thuan ND.   +7 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Emerging Low Detection Limit of Optically Activated Gas Sensors Based on 2D and Hybrid Nanostructures. [PDF]

Nanomaterials (Basel)
Odebowale AA, Abdulghani A, Berhe AM, Somaweera D, Akter S, Abdo S, As'ham K, Saadabad RM, Tran TT, Bishop DP, Solntsev AS, Miroshnichenko AE, Hattori HT.   +12 more
europepmc   +1 more source

The Detection of Two Distinct High Ionization States in a QSO Lyman-Limit Absorption System: Evidence for Hierarchical Galaxy Formation at [CLC][ITAL]z[/ITAL][/CLC] ∼ 3? [PDF]

, 1999
David Kirkman, David Tytler, David Kirkman, David Tytler   +3 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source