Results 111 to 120 of about 3,117,505 (304)
A synthetic antibiotic class with a deeply-optimized design for overcoming bacterial resistance
Nature CommunicationsThe lack of new drugs that are effective against antibiotic-resistant bacteria has caused increasing concern in global public health. Based on this study, we report development of a modified antimicrobial drug through structure-based drug design (SBDD ...
Jin Feng +7 more
doaj +1 more source
Total sleep duration and daytime napping in relation to dementia detection risk: Results from the Million Women Study. [PDF]
Alzheimers Dement, 2023 Wong ATY, Reeves GK, Floud S.
europepmc +1 more source
Detecting Financial Collapse and Ballooning Sovereign Risk
Oxford Bulletin of Economics and Statistics, 2019 AbstractThis paper proposes a new model for capturing discontinuities in the underlying financial environment that can lead to abrupt falls, but not necessarily sustained monotonic falls, in asset prices. This notion of price dynamics is consistent with existing understanding of market crashes, which allows for a mix of market responses that are not ...
Peter C. B. Phillips, Shuping Shi
openaire +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Journal of Analytical Methods in Chemistry, 2018 This paper presents a convenient and sensitive LC-MS/MS method for the simultaneous determination of carbadox and olaquindox residues, including desoxyolaquindox (DOLQ), desoxycarbadox (DCBX), quinoxaline-2-carboxylic acid (QCA), 3-methyl-quinoxaline-2 ...
Heying Zhang +8 more
doaj +1 more source
Mechanisms of the Testis Toxicity Induced by Chronic Exposure to Mequindox
Frontiers in Pharmacology, 2017 Mequindox (MEQ) is a synthetic antimicrobial agent widely used in China since the 1980s. Although the toxicity of MEQ is well recognized, its testis toxicity has not been adequately investigated.
Qianying Liu +9 more
doaj +1 more source
Gastroparesis-Related Symptoms in Patients With Type 2 Diabetes Mellitus: Early Detection, Risk Factors, and Prevalence. [PDF]
Cureus, 2023 Asghar S +5 more
europepmc +1 more source
An Evidence Based Time-Frequency Search Method for Gravitational Waves from Pulsar Glitches
, 2007 We review and expand on a Bayesian model selection technique for the detection of gravitational waves from neutron star ring-downs associated with pulsar glitches.
Franco L M +4 more
core +1 more source
Canadian family physician Medecin de famille canadien, 2010 An undeniable fact of life is the potential risk of suicide. It is an ubiquitous phenomenon and touches every family practice at some time. Evidence indicates that the physician is in the forefront of recognition and management of this alarming and distressing problem.
openaire +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source