Results 101 to 110 of about 1,700,049 (319)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The nature and epidemiology of OqxAB, a multidrug efflux pump
Antimicrobial Resistance and Infection Control, 2019 Background OqxAB efflux pump has been found to mediate multidrug resistance (MDR) in various bacteria over the past decades. The updates on the nature and epidemiology of OqxAB efflux pump need to be fully reviewed to broaden our understanding of this ...
Jun Li +6 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Grain & Oil Science and TechnologyStarch retrogradation is a primary contributor to the staling of bread. The impact of the surfactant glyceryl monostearate (GMS) on the structure and retrogradation characteristics of wheat starch gels was explored during storage at 4 °C for 2 h and 5 d.
Qi Xu +7 more
doaj +1 more source
Early Risk Detection of Anorexia on Social Media [PDF]
, 2018 This paper proposes an approach for the early detection of anorexia nervosa (AN) on social media. We present a machine learning approach that processes the texts written by social media users. This method relies on a set of features based on domain-specific vocabulary, topics, psychological processes, and linguistic information extracted from the users’
Diana Ramírez-Cifuentes +2 more
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
A study on detection of risk factors of a toddler’s fall injuries using visual dynamic motion cues
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The research in this thesis is intended to aid caregivers’ supervision of toddlers to prevent accidental injuries, especially injuries due to falls in the ...
Na, Hana
core
Real-Time Birds Shadow Detection for Autonomous UAVs
, 2023 Autonomous unmanned aerial vehicles (UAVs) are commonly used for wildlife exploration and animal monitoring. Therefore, bird attacks pose a significant challenge to UAVs.
Bouali, Kassem Anis
core