Results 81 to 90 of about 1,700,049 (319)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A Survey of Tax Risk Detection Using Data Mining Techniques

open access: yes, 2023
Tax risk behavior causes serious loss of fiscal revenue, damages the country’s public infrastructure, and disturbs the market economic order of fair competition.
Huixiang Liu   +5 more
core   +1 more source

Risks in Audit and Their Assessment

open access: yesСтатистика України, 2017
Audit activities involve the existence of various risks having implications for a final auditor’s judgment. As a risk can never be reduced to zero, the auditor’s task is in its minimization.
T. O. Kamenska
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins [PDF]

open access: yes, 2020
IMPORTANCE There is an urgent need to improve lung cancer risk assessment because current screening criteria miss a large proportion of cases. OBJECTIVE To investigate whether a lung cancer risk prediction model based on a panel of selected circulating ...
Agudo, Antonio   +1 more
core   +1 more source

Resistance Response and Regulatory Mechanisms of Ciprofloxacin-Induced Resistant Salmonella Typhimurium Based on Comprehensive Transcriptomic and Metabolomic Analysis

open access: yesAntibiotics
Background: Salmonella infections pose a serious threat to both animal and human health worldwide. Notably, there is an increasing trend in the resistance of Salmonella to fluoroquinolones, the first-line drugs for clinical treatment.
Xiaohan Yang   +7 more
doaj   +1 more source

Pesticide residues in bayberry (Myrica rubra) and probabilistic risk assessment for consumers in Zhejiang, China

open access: yesJournal of Integrative Agriculture, 2017
As pesticide residues in bayberry has raised serious concern from the public in China, a monitoring survey was carried out during 2013–2014 and 157 samples were analyzed in total. Twenty-three pesticides were detected among the 44 pesticides analyzed and
Gui-ling YANG   +6 more
doaj   +1 more source

Fine Grained Insider Risk Detection

open access: yesCoRR
We present a method to detect departures from business-justified workflows among support agents. Our goal is to assist auditors in identifying agent actions that cannot be explained by the activity within their surrounding context, where normal activity patterns are established from historical data. We apply our method to help audit millions of actions
Birkett Huber   +5 more
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Development of multi marker electrochemical immunosensors for cardiovascular disease detection [PDF]

open access: yes, 2012
Cardiovascular disease (CVD) is the world’s biggest killer, globally accounting for over 17,5 million deaths annually. Almost half of these deaths are caused by acute myocardial infarction.
Fakanya, Wellington
core  

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