Results 71 to 80 of about 1,375,201 (314)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2019 Recent research on network intrusion detection has focused on correlation-based techniques, which allow one to adapt to continuously changing environments such as the Internet of Things. Despite it being common practice for network intrusion detection to
Gottwalt, Florian +2 more
core +1 more source
IEEE Access, 2020 The wide proliferation of telecommunication technologies in the last decade gives rise to the number of more sophisticated security threats. Software-Defined Networking (SDN) is a new networking architecture that isolates the network control plane from ...
Mohammad A. Aladaileh +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Novel separation and detection techniques for protein analysis
, 2008 Novel separation and detection techniques for protein ...
张玉奎
core
Bivariate Gamma Distributions for Image Registration and Change Detection [PDF]
, 2007 This paper evaluates the potential interest of using bivariate gamma distributions for image registration and change detection. The first part of this paper studies estimators for the parameters of bivariate gamma distributions based on the maximum ...
Florent Chatelain +7 more
core +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Reviews in Cardiovascular MedicineFollowing the global increase in atherosclerotic cardiovascular diseases, the demand for the effective identification of high-risk factors that lead to atherosclerotic plaque rupture and the search for new therapeutic targets has also increased ...
Long Zhang +4 more
doaj +1 more source