From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Electrochemical and Infrared Absorption Spectroscopy Detection of SF6 Decomposition Products
Sulfur hexafluoride (SF6) gas-insulated electrical equipment is widely used in high-voltage (HV) and extra-high-voltage (EHV) power systems. Partial discharge (PD) and local heating can occur in the electrical equipment because of insulation faults ...
Ming Dong +4 more
doaj +1 more source
Relativistic Quantum Information in Detectors-Field Interactions
We review Unruh-DeWitt detectors and other models of detector-field interaction in a relativistic quantum field theory setting as a tool for extracting detector-detector, field-field and detector-field correlation functions of interest in quantum ...
Alsing P M +31 more
core +2 more sources
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Fabricación de un detector de N2O a base de un polímero conductor
Recientes investigaciones demuestran la capacidad de la polianilina (PANI) para detectar la presencia de diferentes gases por medio de cambios en sus propiedades eléctricas; este método resulta de fácil diseño, síntesis directa y costos ...
Luisa Yolanda Quiñones-Montenegro +2 more
doaj
The response of a 300 micron silicon detector to monoenergetic neutrons determined by the use of the Monte Carlo technique [PDF]
The response of a 300 micron thick silicon detector to an incident monoenergetic neutron beam is evaluated by the Monte Carlo method for the cases of both a shielded and a bare detector.
Anno, G., Tahezadeh, M.
core +1 more source
Unrecognized Backscattering in Low Energy Beta Spectroscopy
We present studies on electron backscattering from the surface of plastic scintillator beta detectors. By using a setup of two detectors coaxial with a strong external magnetic field - one detector serving as primary detector, the other as veto-detector ...
Abele +13 more
core +1 more source
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Development of a handheld chlorophyll content detector on wheat and maize leaves based on RGB sensor
Chlorophyll-a (CL-a) and chlorophyll-b (CL-b) are major chlorophyll found in green plants. Determining the CL-a, CL-b, and total chlorophyll (TCL) contents is important to guide crop growth.
Weidong Pan +6 more
doaj +1 more source

