An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Status of the Micro Vertex Detector of the Compressed Baryonic Matter Experiment [PDF]
, 2010 The CBM experiment will investigate heavy-ion collisions at beam energies from 8 to 45 AGeV at the future accelerator facility FAIR. The goal of the experiment is to study the QCD phase diagram in the vincinity of the QCD critical point.
Tischler, Tobias +37 more
core +1 more source
Discrepancy in tidal deformability of GW170817 between the Advanced LIGO twin detectors
Physical Review Research, 2019 We find that the Hanford and Livingston detectors of Advanced LIGO derive a distinct posterior probability distribution of binary tidal deformability Λ[over ̃] of the first binary-neutron-star merger GW170817.
Tatsuya Narikawa +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
High resolution muon tracking with resistive plate chambers [PDF]
, 2012 Following their introduction in the physics community in the early '80s the use of Resistive Plate Chambers (RPCs) as charged particles detectors has constantly increased. Low cost per unit area, good time resolution and easy of operation are some of the
Thomay, Christian +9 more
core +1 more source
Measurements of Higgs Boson Properties using the ATLAS Detector
EPJ Web of Conferences, 2014 Measurements are presented of the production properties, couplings and spin-parity of the recently discovered Higgs-like boson using the decays into boson pairs, γγ, ZZ∗→ 4ℓ and WW∗→ ℓνℓν.
Cao Tingting
doaj +1 more source
Expected resolution limits of x-ray free-electron laser single-particle imaging for realistic source and detector properties. [PDF]
Struct Dyn, 2022 E J +13 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Preparation of Ag/TiO2/ITO UV Detector and Its Photoelectronic Properties
Journal of Aeronautical Materials, 2016 TiO2-based UV detectors with Ag antidot/TiO2/ITO sandwich structure were prepared by RF magnetron sputtering and colloidal crystal template technology.
DAI Songyan +6 more
doaj +1 more source