Results 111 to 120 of about 385,669 (317)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Detectors for digital radiography.

open access: yes, 2004
Illustration of the state-of-the-art development of detectors for digital ...
RUSSO, PAOLO
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Editorial: Silicon radiation detectors: Status and perspectives

open access: yesFrontiers in Physics, 2022
Marco Carminati   +3 more
doaj   +1 more source

A deep learning framework for automated fracture detection and localization in radiographic images using convolutional neural networks

open access: yesFrontiers in Medicine
BackgroundFracture detecting and localizing in radiographic images is essential to enhance the effectiveness of the diagnosis of trauma and allow the image to be interpreted. Despite the potential potential of the deep learning in musculoskeletal imaging,
Jiangdong Lu   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Recovery of radiation damage in CdTe and CdZnTe detectors

open access: yes, 2004
The time and thermal recovery of the spectroscopic capabilities of CdZnTe and CdTe detectors, irradiated with different doses of various ionizing radiations, such as electrons, low-energy neutrons, high-energy neutrons and protons, have been investigated
FRABONI, BEATRICE   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Photosensitive gaseous detectors and their applications

open access: yes, 2004
This paper reviews a large and important class of position sensitive detectors called photosensitive gaseous detectors (PGDs). Their main application rests in the imaging of UV photons. There are however, successful efforts to extend their sensitivity to
Peskov, Vladimir,   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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