Results 131 to 140 of about 378,573 (266)
, 2000 This contribution describes some aspects of the proposed RICH detectors for the LHCb experiment at the CERN LHC collider. Recent activity has focused on identifying which of three candidate photon detectors should be used to construct the LHCb RICH ...
Wotton, S A
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Calorimetric low temperature detectors for mass identification of heavy ions
, 2001 The energy sensitive detection of heavy ions with calorimetric low temperature detectors (CLTDs) is investigated for the energy range E = 0.1-1 MeV/u, commonly used for accelerator mass spectrometry(AMS).
Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany). Bibliothek +3 more
core
, 2003 These lectures review silicon strip detectors and their use in high energy physics experiments. The principles of operation, their performance, the effect of radiation damage, methods of fabrication, their construction into silicon detector modules ...
Honma, Alan, Alan Honma
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Thermal noise reduction for present and future gravitational wave detectors
, 2004 Thermal noise in mirror suspension is and will be the most severe fundamental limit to the low-frequency sensitivity of interferometric gravitational wave detectors currently under construction.
G. Losurdo +16 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Modeling of CdZnTe properties and parameters of γ-radiation detectors based on it
Технологія та конструювання в електронній апаратурі, 2004 By means of computer modeling, the carrier lifetime and mobility, as well as the resistivity of CdxZn1–xTe:Cl material, were investigated in order to determine the optimal combination of these properties and the molar fraction of CdTe that would provide ...
A. I. Kondrik
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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