Results 151 to 160 of about 321,315 (316)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Identifying abnormal traffic congestion on non-signalised urban roads using journey time estimation [PDF]
This paper describes a technique for estimating vehicle journey times on non-signalised roads using 250-ms digital loop-occupancy data produced by single inductive loop detectors.
Morris, Ray +3 more
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Novel photo-detectors and photo-detector systems
7 pages, 6 figures, prepared for Position Sensitive Detectors ...
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Calorimetric low temperature detectors for mass identification of heavy ions [PDF]
The energy sensitive detection of heavy ions with calorimetric low temperature detectors (CLTDs) is investigated for the energy range E = 0.1-1 MeV/u, commonly used for accelerator mass spectrometry(AMS).
Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany). Bibliothek +3 more
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Modeling of CdZnTe properties and parameters of γ-radiation detectors based on it
By means of computer modeling, the carrier lifetime and mobility, as well as the resistivity of CdxZn1–xTe:Cl material, were investigated in order to determine the optimal combination of these properties and the molar fraction of CdTe that would provide ...
A. I. Kondrik
doaj
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

