Results 91 to 100 of about 93,770 (286)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Comparison of feature point detectors for multimodal image registration in plant phenotyping.

PLoS ONE, 2019
With the introduction of multi-camera systems in modern plant phenotyping new opportunities for combined multimodal image analysis emerge. Visible light (VIS), fluorescence (FLU) and near-infrared images enable scientists to study different plant traits ...
Michael Henke, Astrid Junker, Kerstin Neumann, Thomas Altmann, Evgeny Gladilin   +4 more
doaj   +1 more source

Particle identification via transition radiation and detectors

, 2000
Transition radiation detectors show great promise for the purposes of lepton identification in existing and future experiments in high- energy physics such as HERA-B, ATLAS, ALICE in high-luminosity environment.
V. Egorytchev, Egorytchev, V, Aplin, S J, V. Saveliev, S.J. Aplin, Saveliev, V   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Robust electron counting for direct electron detectors with the Back-propagation counting method

npj Computational Materials
Electron microscopy (EM) is a foundational tool for directly assessing the structure of materials. Recent advances in direct electron detectors have improved signal-to noise ratios via single-electron counting.
Joshua Renner, Matthew A. Wright, Kristofer Bouchard, Bruce E. Cohen, Peter Ercius, Azriel Goldschmidt, Cassio C. S. Pedroso, Ambarneil Saha, Peter Denes   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Advances in High-Z semiconductor radiation detectors at BNL

Frontiers in Detector Science and Technology
Semiconductor radiation detectors play a crucial role in scientific research and technological applications, with materials typically categorized as low- or high-Z depending on their atomic numbers and densities.
G. Pinaroli, A. E. Bolotnikov, M. Bouckicha, F. Capocasa, L. Cultrera, A. K. Rumaiz, E. Tamura, G. A. Carini   +7 more
doaj   +1 more source

Development of innovative silicon radiation detectors

, 2013
Silicon radiation detectors fabricated at the IMB-CNM (CSIC) Clean Room facilities using the most innovative techniques in detector technology are presented in this thesis.
Balbuena, JuanPablo
core  

Correction of Dopant Concentration Fluctuation Effects in Silicon Drift Detectors [PDF]

, 2000
Dopant fluctuations in silicon wafers are responsible for systematic errors in the determination of the particle crossing point in silicon drift detectors.
Wheadon, R, Tosello, F, B. S. Nilsen, Bondila, M, Giubellino, P, Nilsen, B S, Piemonte, C, Vacchi, A, Bonvicini, V, A. Rashevsky, F. Tosello, V. Bonvicini, P. Giubellino, E. Crescio, D. Nouais, Cerello, P G, R. Hernandez Montoya, Rachevsky, A, Nouais, D, Piemonte, Claudio, Montaño-Zetina, L M, L. M. Montano, P. Cerello, Kolojvari, A A, A. Kolojvari, M. Bondila, R. Wheadon, Crescio, E, A. Vacchi, Hernández-Montoya, R   +29 more
core  

Commissioning and performance of the GE1/1 slice test detectors

, 2018
The performance of the CMS muon system, as it was instrumented in Run 1, will be deeply called into questions in the next few years. The foreseen increase in luminosity of LHC, up to 5 times the nominal value, will induce a huge increase of the pileup ...
Vai, Ilaria
core   +1 more source