Results 111 to 120 of about 9,359 (237)

Insulin degludec is not associated with a delayed or diminished response to hypoglycaemia compared with insulin glargine in type 1 diabetes: a double-blind randomised crossover study [PDF]

, 2013
Aims/hypothesis: Insulin degludec (Des(B30)LysB29(γ-Glu Nε-hexadecandioyl) human insulin; IDeg) is a new basal insulin with an ultra-long flat action profile.
AE Gold, AJ Garber, B Raju, B Zinman, BM Frier, CG Fanelli, CR Bowie, D Wechsler, F Smeeton, I Jonassen, IJ Deary, International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, KI Birkeland, O Tschritter, P Galassetti, P Rossetti, PA Goldberg, RE Ratner, RE Ratner, RJ McCrimmon, RM Reitan, RT Wilkinson, S Dagogo-Jack, S Heller, S Heller, SCL Gough, SN Davis, T Heise, UK Hypoglycaemia Study Group, V McAulay, World Medical Association   +30 more
core   +2 more sources

Evidence review : liraglutide for the treatment of type 2 diabetes [PDF]

, 2011
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of liraglutide in the treatment of type 2 diabetes mellitus, based upon the manufacturer’s submission to the National Institute
Cummins, E. (Ewen), HASH(0x5574f4171138), Royle, Pamela, Shyangdan, D. (Deepson), Waugh, Norman   +4 more
core  

Effect of Insulin Detemir (Levemir®) on Risk of Hypoglycaemia and Glycaemic Parameters: Experience from Real Life Practice in Indonesian Patients with Diabetes Mellitus

Journal of the ASEAN Federation of Endocrine Societies
Objective. To evaluate the safety and efficacy of insulin detemir in patients with diabetes mellitus in Indonesia.   Methods. This was a multi-centre, prospective, 12-week observational study in patients with diabetes mellitus conducted in Indonesia. 
Pradana Soewondo, Anand Jain
doaj   +1 more source

Cost-effectiveness of insulin analogs from the perspective of the Brazilian public health system

Brazilian Journal of Pharmaceutical Sciences, 2017
Human insulin is provided by the Brazilian Public Health System (BPHS) for the treatment of diabetes, however, legal proceedings to acquire insulin analogs have burdened the BPHS health system.
Maurílio de Souza Cazarim, João Paulo Vilela Rodrigues, Estael Luzia Coelho da Cruz-Cazarim, Lorena Rocha Ayres, Leonardo Régis Leira Pereira   +4 more
doaj   +1 more source

Insulin analogues versus human insulin in type 1 diabetes: direct and indirect meta-analyses of efficacy and safety

Brazilian Journal of Pharmaceutical Sciences, 2013
All patients with Diabetes Mellitus (DM) receive insulin therapy. In this study, we evaluated the efficacy, safety and tolerability of human insulin and insulin analogues.
Andréia Cristina Conegero Sanches, Cassyano Januário Correr, Rafael Venson, Patrícia Rodrigues Gonçalves, Mariana Martins Garcia, Mário Sérgio Piantavini, Roberto Pontarolo   +6 more
doaj   +1 more source

A 26-week, randomized trial of insulin detemir versus NPH insulin in children and adolescents with type 2 diabetes (iDEAt2)

European Journal of Pediatrics, 2018
There are limited studies evaluating the safety and efficacy of treatments in young people with type 2 diabetes (T2D). This study compared the efficacy and safety of insulin detemir versus neutral protamine Hagedorn (NPH) insulin, both in combination ...
M. Wheeler, M. Barrientos-Pérez, F. Lo, Bo Liang, A. Lunsford, Ólöf Thórisdóttir, N. Zuckerman-Levin   +6 more
semanticscholar   +1 more source

The Efficacy of Insulin Detemir Versus Neutral Protamine Hagedorn Insulin in Treatment of Gestational Diabetes Mellitus During Pregnancy

Pakistan Journal of Medical Research
Background: The gestational diabetes mellitus (GDM) is one of the most common medical conditions during pregnancy. Insulin is considered to be safe in pregnancy.
Rukhsana Babar, Amna Mazhar, Diljan Rehman, Sadia Salman, Azka Tariq, Hatim Rehman   +5 more
doaj   +2 more sources

Glargine and detemir: Safety and efficacy profiles of the long-acting basal insulin analogs

Drug, Healthcare and Patient Safety, 2010
Kitty Poon, Allen B KingDiabetes Care Center, Salinas, CA, USAAbstract: Diabetes mellitus is a growing public health concern in the US and worldwide. Insulin therapy is the cornerstone of diabetes therapy, and the use of basal insulins will increase as ...
Kitty Poon, Allen B King
doaj  

Basal insulin therapy in patients with type 2 diabetes mellitus and poor control of glycemia by oral hypoglycemic agents: results of direct comparative study of insulin analogs Lantus and Levemir

Сахарный диабет, 2010
Aim. To compare efficiency of two regimes of basal therapy with human insulin analogs glargin (Lantus) once daily and detemir (Levemir) twicedaily based on their hypoglycemic action ...
Alsu Gafurovna Zalevskaya, Nelli Il'inichna Verbovaya, Tatiana Igorevna Rodionova, Olga Konstantinovna Vikulova, Marina Vladimirovna Shestakova   +4 more
doaj   +1 more source

Basal insulin analogues in the diabetes mellitus type 2 control — economic aspects

Качественная клиническая практика, 2018
Economic aspects of insulin analogues — glargine and detemir — in the control of diabetes mellitus type 2 (DM 2) has been prepared in according to needs of the Russian health care system.
D. Yu. Belousov, E. V. Afanasyeva
doaj