Results 81 to 90 of about 4,485 (161)

Waist circumference reduction after insulin Detemir therapy in type 2 diabetes patients previously treated with NPH.

, 2009
Background and aims: Abdominal weight may increase vascular complication risk. Insulin detemir reduces weight gain in comparison with NPH and insulin glargine.
GATTI, ALESSANDRA, ADINOLFI V, MANDOSI, ELISABETTA, FALLARINO, Mara, ROSSETTI, MARCO, MORANO, Susanna, ROSSETTI M   +6 more
core   +1 more source

Differences in Effect of Insulin Detemir and NPH Insulin on Glucose and Lipid Metabolism. [PDF]

, 2020
Insulin detemir has a 14C fatty acid chain, which associates with free fatty acid binding sites on albumin. Capillary endothelial cells in adipose tissue and muscle may limit transfer of insulin detemir from the circulation into the extravascular ...
Hodern, Sara Victoria Margaret.
core  

Adiponectin, Leptin, and Leptin Receptor in Obese Patients with Type 2 Diabetes Treated with Insulin Detemir

Molecules, 2017
The aim of the present study is to quantitatively assess the expression of selected regulatory molecules, such as leptin, leptin receptor, and adiponectin in the blood of obese patients with type 2 diabetes both before treatment and after six months of ...
Paweł Olczyk, Robert Koprowski, Katarzyna Komosinska-Vassev, Agnieszka Jura-Półtorak, Katarzyna Winsz-Szczotka, Kornelia Kuźnik-Trocha, Łukasz Mencner, Alicja Telega, Diana Ivanova, Krystyna Olczyk   +9 more
doaj   +1 more source

Basal insulin analogues in the diabetes mellitus type 2 control — economic aspects

Качественная клиническая практика, 2018
Economic aspects of insulin analogues — glargine and detemir — in the control of diabetes mellitus type 2 (DM 2) has been prepared in according to needs of the Russian health care system.
D. Yu. Belousov, E. V. Afanasyeva
doaj  

The Efficacy of Insulin Detemir Versus Neutral Protamine Hagedorn Insulin in Treatment of Gestational Diabetes Mellitus During Pregnancy

Pakistan Journal of Medical Research
Background: The gestational diabetes mellitus (GDM) is one of the most common medical conditions during pregnancy. Insulin is considered to be safe in pregnancy.
Rukhsana Babar, Amna Mazhar, Diljan Rehman, Sadia Salman, Azka Tariq, Hatim Rehman   +5 more
doaj   +2 more sources

Metabolic parameters of continuously applied regular insulin or insulin detemir by using micro-osmotic pumps.

, 2016
(A) Plasma insulin levels following implantation of micro-osmotic pumps containing either regular insulin, insulin detemir or saline. (B-D) Blood glucose concentrations (B), plasma glucagon levels (C) and body weight (D) of mice implanted with micro ...
Anita M. Hennige (36355), Andreas Fritsche (36362), Tina Sartorius (125894), Hans-Ulrich Häring (36363)   +3 more
core   +1 more source

Investigations of albumin-insulin detemir complexes using molecular dynamics simulations and free energy calculations

, 2020
Insulin detemir is a lipidated insulin analogue that obtains a half-life extension by oligomerization and reversible binding to human serum albumin. In the present study, the complex between a detemir hexamer and albumin is investigated by an integrative
Bukrinski, Jens T., Ryberg, Line Abildgaard, Peters, Guenther, Sønderby, Pernille, Peters, Günther H. J., Ryberg, Line A., Harris, Pernille   +6 more
core   +1 more source

Comparison of insulin lispro protamine suspension and insulin detemir in basal-bolus therapy in patients with Type 1 diabetes

, 2010
P>AimsThe efficacy of two basal insulins, insulin lispro protamine suspension (ILPS) and insulin detemir, was compared in basal-bolus regimens in Type 1 diabetes.MethodsIn this 32-week, multinational, parallel-group, randomized, controlled trial, adult ...
A. R. Chacra, J. Chan, M. Kipnes, Chacra, A. R. [UNIFESP], Ilag, L. L., Sarwat, S., L. L. Ilag, Chan, J., Kipnes, M., Giaconia, J., S. Sarwat, J. Giaconia, COMPLETE T1D Investigators   +12 more
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Differential Effects of Adiposity on Pharmacodynamics of Basal Insulins NPH, Glargine, and Detemir in Type 2 Diabetes mellitus.

, 2011
OBJECTIVETo assess the role of adiposity on the pharmacodynamics of basal insulins NPH, detemir, and glargine in type 2 diabetes mellitus (T2DM), as estimated by glucose infusion rate (GIR) and endogenous glucose production (EGP) rate in the euglycemic ...
BOLLI, Geremia Brunetto, LUCIDI, Paola, Rossetti P, Cioli P, FANELLI, Carmine Giuseppe, PORCELLATI, Francesca, Candeloro P, MARINELLI ANDREOLI, ANNA, Marzotti S   +8 more
core   +1 more source

Weight-Sparing Effect Of Insulin Detemir: A Consequence Of Central Nervous System-Mediated Reduced Energy Intake?

, 2015
Insulin therapy is often associated with adverse weight gain. This is attributable, at least in part, to changes in energy balance and insulin's anabolic effects.
Danne, T., Thalange, N., Robertson, K., Yildiz, B., Hermansen, K., Vasselli, J. R., Russell-Jones, D., Niswender, K., Haering, H. U.   +8 more
core   +1 more source