Results 111 to 120 of about 159,129 (259)

Maximum Stability Point Tracking Stabilizes Wide‐Bandgap Mixed‐Halide Perovskite Solar Cells

open access: yesAdvanced Energy Materials, EarlyView.
A maximum stability point tracking (MSPT) strategy suppresses charge trapping‐induced halide segregation, enabling wide‐bandgap perovskite solar cells to achieve significantly enhanced operational stability compared to conventional maximum power point tracking (MPPT).
Seongheon Kim   +7 more
wiley   +1 more source

Guidelines for High‐Throughput Screening for Natural Products With Anti‐Aging Activity Based on Drosophila Intestinal Homeostasis

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
ABSTRACT Aging represents a critical risk factor for chronic diseases, driving an urgent demand for interventions promoting healthy longevity. This study establishes standardized guidelines for high‐throughput screening (HTS) of anti‐aging natural products using Drosophila melanogaster, leveraging its intestinal homeostasis as a biomarker.
Xiao Sheng, Lei Zhang
wiley   +1 more source

Detergent Conjugation Decouples Chlorpromazine Solubility from Antibacterial Activity against Bacteria Relevant for Gut Microbiota. [PDF]

open access: yesBioconjug Chem
Seewald M   +7 more
europepmc   +1 more source

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

open access: yesAdvanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song   +6 more
wiley   +1 more source

A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles

open access: yesAngewandte Chemie, EarlyView.
The fischerazoles, unusual cyanobacterial chlorinated lipopeptides are reported. During their biosynthesis, a linear fatty acyl‐acyl carrier protein (ACP) precursor is rearranged through the action of the S‐adenosyl‐methionine (SAM)‐dependent methyltransferase FshF, to generate a pendant vinyl group.
Sandra A. C. Figueiredo   +8 more
wiley   +2 more sources

Haptic In‐Sensor Computing Device Based on CNT/PDMS Nanocomposite Physical Reservoir

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Using a porous carbon nanotube‐polydimethylsiloxane nanocomposite, a sensor array integrated with a physical reservoir computing paradigm capable of in‐sensor computing is demonstrated. The device is able to classify between nine objects with an accuracy above 80%, opening the possibility for low‐power sensing/computing for future robotics.
Kouki Kimizuka   +7 more
wiley   +1 more source

A Comprehensive 19F NMR Framework for Fragment‐Based Drug Discovery: The Validated Screening Library OpenFL600 and Efficient Affinity Ranking by CSAR

open access: yesAngewandte Chemie, EarlyView.
NMR screening is a powerful method for hit detection in drug‐discovery. We designed and validated the OpenFL600 19F$^{19}{\rm F}$ NMR library to probe diverse targets, including RNA, GPCRs, kinases, and proteases. This library yields target‐specific ligands without generating promiscuous binders.
Simon H. Rüdisser   +16 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy