Results 111 to 120 of about 158,894 (263)
Advanced Science, EarlyView.This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu +17 more
wiley +1 more source
Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma
Advanced Science, EarlyView.ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba +25 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.An experimentally validated optoelectronic device model is presented to describe the efficiency and roll‐off behavior of single‐layer TADF OLEDs. By coupling charge transport, exciton dynamics, and optical outcoupling, the model reproduces the External Quantum Efficiency (EQE) across different emission layer thicknesses and temperatures, offering ...
Jawid Nikan +4 more
wiley +1 more source
Dry‑Contact Trimming for All‑Perovskite Tandem Solar Cells via Solid‑Solution Homogenization
Advanced Energy Materials, EarlyView.Narrow‐bandgap Sn–Pb perovskites are promising bottom absorbers for all‐perovskite tandems but suffer from Sn‐rich surfaces and depth‐dependent lattice/compositional inhomogeneity. Layered‐perovskite‐assisted dry‐contact trimming removes Sn‐rich surface species and reconfigures the Sn–Pb absorber, enabling efficient charge collection, reduced voltage ...
Woocheol Han +10 more
wiley +1 more source
Advanced Energy Materials, EarlyView.An alcohol‐adduct‐mediated strategy is employed to stabilize tin isopropoxide for the formation of a homogeneous double electron transport layer (ETL) incorporating SnO2 nanoparticles (NPs). This double‐ETL exhibits improved optical and charge‐transport properties due to reduced defect density and better energy level alignment, resulting in high ...
You‐Hyun Seo +10 more
wiley +1 more source
Lattice Coherency‐Driven (111)‐Oriented Wide Bandgap Perovskite Films
Advanced Energy Materials, EarlyView.Methylammonium lead chloride (MAPbCl3)‐derived seed templates regulate wide‐bandgap perovskite crystallization through coupled thermodynamic and kinetic effects. Lattice‐coherent templating lowers the energy cost for (111) epilayer growth, while growth retardation controls crystallization kinetics, ultimately producing highly crystalline face‐up (111 ...
Yu‐Na Lee +5 more
wiley +1 more source
High‐Performance Noble‐Metal‐Free Perovskite Solar Cells Enabled by MoOX/Cr/Al Multilayer Electrodes
Advanced Energy Materials, EarlyView.Cost‐effective perovskite solar cells (PSCs) are developed using a noble‐metal‐free MoOX/Cr/Al multilayer electrode. The devices achieve a power conversion efficiency (PCE) of 25.6%, competitive with that of Au‐based devices (26.3%), and a 25.5 cm2 mini‐module shows 21.3% PCE.
Wooyeon Kim +7 more
wiley +1 more source
Guidelines for Detecting the Foodborne Antibiotic‐Resistant Bacteria
AgriFood: Journal of Agricultural Products for Food, EarlyView.ABSTRACT Foodborne antibiotic‐resistant bacteria threaten global public health and the economic. Standardized detection methods are crucial for effective prevention and control. Researchers encounter difficulties in choosing suitable techniques due to the variety of available approaches and the intricate nature of resistance mechanisms.
Yuanye Zeng, Fengxia Yang
wiley +1 more source
AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
Advanced Intelligent Discovery, EarlyView.To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source