Results 121 to 130 of about 159,129 (259)

Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System

Annals of Neurology, EarlyView.
Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti, Nicolas R. Barthélemy, Kanta Horie, Cindy V. Ly, Kaleigh F. Roberts, Srinivas Koutarapu, Richard J. Perrin, Erin E. Franklin, Chiara Pedicone, Joshua Orrick, Justin Melendez, Timothy M. Miller, Chihiro Sato, Nupur Ghoshal, Alison M. Goate, Celeste M. Karch, Randall J. Bateman, Soumya Mukherjee   +17 more
wiley   +1 more source

Longer theoretical length of cut in whole-plant sorghum silage increased feed intake and starch digestibility in growing beef steers. [PDF]

Transl Anim Sci
Fernandez F, Tarnonsky F, Rodriguez-Guiñazu A, Arias R, Delgado-Caffé J, Abdelhadi LO, DiLorenzo N.   +6 more
europepmc   +1 more source

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk

Annals of Neurology, EarlyView.
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber, Ricardo Hernández Arriaza, Dylan Reil, Manon Muntaner, Junyoung Park, Benjamin Grenier‐Boley, Marc Hulsman, Philippe Amouyel, Céline Bellenguez, Camille Charbonnier, Jean‐François Deleuze, Orio Dols‐Icardo, John Hardy, Henne Holstege, Gaël Nicolas, Simon Mead, Michael Wagner, Alfredo Ramirez, Rebecca Sims, John van Swieten, Julie Willams, Jean‐Charles Lambert, Chaitan Khosla, Yann Le Guen, Michael D Greicius   +24 more
wiley   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

The quality of artificial grasslands in alpine regions is controlled by crop photosynthesis under different fertilization conditions. [PDF]

Sci Rep
Feng TX, Li F, Lin WS, Zhang L, Xiang XM, Wei XJ, De KJ.   +6 more
europepmc   +1 more source

High molecular weight insoluble parkin in the substantia nigra of patients with idiopathic Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Tremblay C, Pshevorskiy L, Cottez RJ, Denis HL, Emond V, Morissette M, Rajput AH, Di Paolo T, Rajput A, Calon F.   +9 more
europepmc   +1 more source

Electrical Property Enhancement of a Breast-Fat-Equivalent Phantom for Microwave Mammography. [PDF]

Bioengineering (Basel)
Inada K, Nozaki Y, Yamamoto T.
europepmc   +1 more source

Backbone Nitrogen Substitution Probes the Role of Glycine Residues at GxxxG Interfaces in Transmembrane Helices. [PDF]

Biochemistry
Thomas D, Gu F, Newberry RW.
europepmc   +1 more source

NIRS for predicting Brown Swiss heifer diet composition on mixed pastures in the Amazon region. [PDF]

Trop Anim Health Prod
Mejía FL, Yoplac I, Flores ER, Paucar Y, Saucedo-Uriarte JA, Bardales W, Vasquez HV, Ñaupari J.   +7 more
europepmc   +1 more source