Results 121 to 130 of about 214,333 (261)
Detergent-Aided Polymersome Preparation
, 2016 Until now, most preparative methods used to form polymeric vesicles involve either organic cosolvents or sonication. In this communication, we demonstrate for the first time a detergent-aided method to produce polymersomes.
Hana Robson Marsden (2306674) +5 more
core +1 more source
Advanced Science, EarlyView.This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree +18 more
wiley +1 more source
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Advanced Science, EarlyView.Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
Advanced Science, EarlyView.Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang +15 more
wiley +1 more source
, 2018 Kawat ortodonti nikel-titanium (NiTi) merupakan salah satu kawat yang sering digunakan pada tahap awal dalam perawatan ortodonti. Kawat ortodonti nikel-titanium (NiTi) ini berpotensi mengalami pelepasan ion nikel.
Lubis, Nadia Tamari
core
Advanced Science, EarlyView.This work employs a hybrid hole transport layer to enhance hole transport efficiency, resulting in improved performance for the final device. It achieves an external quantum efficiency of 6.68%, a circularly polarized electroluminescence asymmetry factor of 0.026, and a high luminance of 14,370 cd/cm2, representing the highest luminance reported to ...
Fengqi Qiu +8 more
wiley +1 more source
Carbon Nanotube/Detergent Interactions via Coarse-Grained Molecular Dynamics
, 2007 Detergent interactions with carbon nanotubes are of potential importance in a number of bionanotechnology applications. We investigate the interaction of lysophospholipids with single-walled carbon nanotubes via coarse-grained molecular dynamics.
E. Jayne Wallace (1659106) +1 more
core +1 more source
Advanced Science, EarlyView.An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He +6 more
wiley +1 more source
, 2014 VVG staining for native uterine tissue (A) and decellularized uterine tissue by 0.1%SDS detergent for 1 hour (B), 1%SDS detergent for 1 hour (C), 1%SDS detergent for 2 hours (D), HHP10-4 (E), HHP10-37 (F), HHP30-4 (G), HHP30-37 (H), 1%Triton-X detergent ...
Akio Kishida (603893) +9 more
core +1 more source
Advanced Science, EarlyView.DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng +16 more
wiley +1 more source