Results 121 to 130 of about 150,348 (305)

Product Service Systems and Sustainability: Opportunities for Sustainable Solutions [PDF]

open access: yes, 2002
Given that the concept of PSS is beginning to 'catch on' and gain attention, it is time for UNEP to contribute to, and influence the progress of PSS, to ensure that in concept and application it incorporates the idea of sustainability.
Carlo Vezzoli, Ezio Manzini
core  

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

Strawberry Protease as a Laundry Detergent Additive Candidate: Immobilization, Compatibility Study with Detergent Ingredients, and Washing Performance Test

open access: yesGlobal Challenges
The potential of strawberry‐derived protease as a component of laundry detergent is investigated. The compatibility of the enzyme with various surfactants, oxidizing agents, and commercial detergents is tested.
Esma Hande Alici, Gulnur Arabaci
doaj   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

open access: yesAdvanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh   +14 more
wiley   +1 more source

SDS Depletion from Intact Membrane Proteins by KCl Precipitation Ahead of Mass Spectrometry Analysis

open access: yesProteomes
Background: Membrane proteins are preferentially solubilized with sodium dodecyl sulfate (SDS), which necessitates a purification protocol to deplete the surfactant prior to mass spectrometry analysis.
Tania Iranpour   +4 more
doaj   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

open access: yesAdvanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen   +12 more
wiley   +1 more source

Microbial Colonization, Biofilm Formation, and Malodour of Washing Machine Surfaces and Fabrics and the Evolution of Detergents in Response to Consumer Demands and Environmental Concerns

open access: yesAntibiotics
Bacterial attachment and biofilm formation are associated with the contamination and fouling at several locations in a washing machine, which is a particularly complex environment made from a range of metal, polymer, and rubber components. Microorganisms
Patricia Osta-Ustarroz   +2 more
doaj   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao   +14 more
wiley   +1 more source

SNAC-tag for sequence-specific chemical protein cleavage. [PDF]

open access: yes, 2019
Site-specific protein cleavage is essential for many protein-production protocols and typically requires proteases. We report the development of a chemical protein-cleavage method that is achieved through the use of a sequence-specific nickel-assisted ...
Dang, Bobo   +5 more
core  

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