Results 91 to 100 of about 1,516,160 (291)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

deterioration

open access: yes
Citation: 'deterioration' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13902 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Aging concrete structures: a review of mechanics and concepts

open access: yesDie Bodenkultur, 2018
The safe and cost-efficient management of our built infrastructure is a challenging task considering the expected service life of at least 50 years. In spite of time-dependent changes in material properties, deterioration processes and changing demand by
Wan-Wendner Roman
doaj   +1 more source

Teardown analysis for detecting shelf-life degradation [PDF]

open access: yes, 1971
Analysis is guideline in examining component materials, analytically determining physical properties and chemical compositions, and developing control data necessary for ascertaining effects of environments and their influence on deterioration and ...
Eckstein, A. S.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Ultra-early neurological deterioration following a brain arteriovenous malformation rupture

open access: yesFrontiers in Neurology
PurposeThis study aims to explore the impact of ultra-early neurological deterioration (U-END) on the outcome (mortality and poor neurological status) following a brain arteriovenous malformation (BAVM) rupture and identify determinants of U-END ...
Eimad Shotar   +22 more
doaj   +1 more source

Embedded Smart Antenna for Non-Destructive Testing and Evaluation (NDT&E) of Moisture Content and Deterioration in Concrete

open access: yesSensors, 2019
Concrete failure will lead to serious safety concerns in the performance of a building structure. It is one of the biggest challenges for engineers to inspect and maintain the quality of concrete throughout the service years in order to prevent ...
Kah Hou Teng   +6 more
doaj   +1 more source

Single machine scheduling with general positional deterioration and rate-modifying maintenance [PDF]

open access: yes, 2012
We present polynomial-time algorithms for single machine problems with generalized positional deterioration effects and machine maintenance. The decisions should be taken regarding possible sequences of jobs and on the number of maintenance activities to
Rustogi, Kabir, Strusevich, Vitaly A.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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