Results 101 to 110 of about 1,516,160 (291)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Remote Sensing and Environmental Monitoring Analysis of Pigment Migrations in Cave of Altamira’s Prehistoric Paintings

Remote Sensing
The conservation of Cultural Heritage in cave environments, especially those hosting cave art, requires comprehensive conservation strategies to mitigate degradation risks derived from climatic influences and human activities.
Vicente Bayarri, Alfredo Prada, Francisco García, Carmen De Las Heras, Pilar Fatás   +4 more
doaj   +1 more source

Investigation to identify paint coatings resistive to microorganism growth [PDF]

, 1971
All selected coatings contain nutrients that support microbial growth and survival. Incorporation of microbiocidal agents into coatings more susceptible to attack is recommended for improved inhibition of microorganism growth and for increased protection
Cooper, C. W., Kemp, H. T.
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Performance deterioration: An airline perspective [PDF]

Certain features of engine design and installation are clearly demonstrating important advantages in engine performance retention. Bearing arrangement no doubt has an important role in performance retention.
Andersen, N. B.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Condition Assessment of Reinforced Concrete Bridges: Current Practice and Research Challenges

Infrastructures, 2018
One quarter of bridges in Canada and the United States need repair. The present study provides a critical overview of the state-of-the-art existing condition assessment techniques for reinforced concrete bridges, with an emphasis on current practice in ...
Tarek Omar, Moncef L. Nehdi
doaj   +1 more source

Infrared detection of concrete deterioration [PDF]

Infrared detection of concrete ...
Arnold, R. H., Furr, H. L., Rouse, J. W., Jr.   +2 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

High-temperature ceramic-to-ceramic seals [PDF]

, 1972
Noble-metal braze applied to appropriately prepared zirconia parts produces a gas-tight, durable seal that can withstand temperature of 825 C for over 2000 hours without ...
Smart, W.
core   +1 more source