Results 61 to 70 of about 790,455 (292)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Determinacy of determinantal varieties [PDF]
manuscripta mathematica, 2018 10 ...
Imran Ahmed, Maria Aparecida Soares Ruas
openaire +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Innovaciones organizativas y sus determinantes: Un estudio de casos comparativo
Tecnología en Marcha, 2017 La presente investigación es de tipo cualitativo; estábasada en la técnica de estudio de casos. Se consultó la teoría fundamentada con el objetivo de analizar los factores determinantes de las innovaciones organizativas en empresas del sector de ...
Marjorie Sojo-Castro +1 more
doaj +1 more source
Применение наноматериалов и нанотехнологий в строительстве [PDF]
, 2011 Se estudian los determinantes de la heterogeneidad observada en la flexibilidad de precios, empleando los resultados encontrados en una encuesta.
Иванова, С.О +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Confianza en el Congreso y opinión pública: el caso mexicano
Revista Mexicana de Ciencias Políticas y Sociales, 2018 La falta de confianza en las instituciones de la democracia puede provocar que los ciudadanos “apuesten” por un retorno hacia un régimen autoritario. En México, ¿cuánta confianza tiene el ciudadano en el Congreso, comparado con otras instituciones?
Ricardo R. Gómez Vilchis
doaj +1 more source
Entre a modificação e a quantificação
Domínios de Lingu@gem, 2020 O objetivo deste artigo é explicar o comportamento de adjetivos que estão funcionando ora como um modificador ora como um determinante no Português Brasileiro (PB).
Ana Paula Quadros Gomes +1 more
doaj +1 more source
, 2023 We survey determinantal singularities, their deformations, and their topology. This class of singularities generalizes the well studied case of complete intersections in several different aspects, but exhibits a plethora of new phenomena such as for instance non-isolated singularities which are finitely determined, or smoothings with low connectivity ...
Frühbis-Krüger, Anne, Zach, Matthias
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source