Results 81 to 90 of about 171,305 (308)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Las determinantes de la industria metalúrgica básica del hierro y el acero en el Perú: 2000-2020
Revista del Instituto de Investigación de la Facultad de Minas, Metalurgia y Ciencias GeográficasSiendo la industrialización de carácter fundamental para posibilitar el desarrollo económico sostenido de la economía de un país, esta investigación de revisión plantea como objetivo central el señalar, cuáles han sido las determinantes de la ...
Juan José Manuel Ospino Edery +1 more
doaj +1 more source
FATORES DETERMINANTES NA ESCOLHA DE CURSOS DE PÓS-GRADUAÇÃO LATO SENSU [PDF]
, 2013 A profissionalização do ramo educacional faz com que as IES busquem informações sobre atratividade de seus cursos, ou seja, quais fatores são determinantes para a escolha por essa Instituição.
Tauil, Amire, Mainardes, Emerson Wagner
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Determinante antirasističnega izobraževanja
Andragoška spoznanja, 2017 Vnovični vzpon fašizma v podobi »alt-desnice« kaže, da se liberalno antirasistično izobraževanje in propagiranje večkulturne družbe nista pokazali za posebej uspešni, navkljub velikim finančnim vložkom in institucionalnim prizadevanjem. Borni rezultati so posledica konceptualne redukcije rasizma na psiho- loško raven, na kognitivni spodrsljaj, ki ga ...
openaire +4 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Kronecker Determinantal Point Processes
CoRR, 2016 Determinantal Point Processes (DPPs) are probabilistic models over all subsets a ground set of $N$ items. They have recently gained prominence in several applications that rely on "diverse" subsets. However, their applicability to large problems is still limited due to the $\mathcal O(N^3)$ complexity of core tasks such as sampling and learning.
Mariet, Zelda Elaine, Sra, Suvrit
openaire +5 more sources
Determinantes interrogativos y exclamativos [PDF]
, 2013 Material explicativo sobre os determinantes explicativos e interrogativos no ...
Giracca, Mirella Nunes +5 more
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source