Results 131 to 140 of about 1,575,474 (314)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
National Collaborating Centre for Determinants of Health. (2012). Learning together – Population health status reporting ethics and best practices for access and use of external data. Antigonish, NS: Author.
Dyck, Lesley
core
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Social determinants of Australia's First Peoples' health : a multi-level empowerment perspective
Australia’s First Peoples are leading world citizens in the struggle for health equity and justice. They are leaders in culturally responsive, safe and respectful social support services, social and emotional well-being promotion and comprehensive ...
Fitzpatrick, Sally (R18380) +2 more
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CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Determinants of economic growth: will data tell? [PDF]
Many factors inhibiting and facilitating economic growth have been suggested. Will international income data tell which matter when all are treated symmetrically a priori?
Ciccone, Antonio, Jarociński, Marek
core
Adult Working Group : Cross-national Consultations on Health and Learning [PDF]
Adult Working Group. (2007). Adult working group: Cross-national consultations on health and learning. Antigonish, NS: National Collaborating Centre for Determinants of Health, St.
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Psychological Determinants of Health Behavior
This review provides a critical overview of current evidence on psychological health behavior determinants and its value in informing intervention and future determinants research.
Hagger, Martin S, Hagger, Martin S.
core +1 more source

