Results 151 to 160 of about 1,261,069 (318)
Leadership for health equity : Working intersectorally and engaging the community in Western Health
, 2014 National Collaborating Centre for Determinants of Health. (2014). Leadership for health equity: Working intersectorally and engaging the community in Western Health. Antigonish, NS: National Collaborating Centre for Determinants of Health, St.
Daghofer, Diana
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2012 MacLeod, Anna & Betker, Claire (2012). Antoinette’s Story: An introduction to an early child development model of care and post-natal home visiting scenario.
Betker, Claire, MacLeod, A.
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 2012 National Collaborating Centre for Determinants of Health. (2012). Learning together – Population health status reporting ethics and best practices for access and use of external data. Antigonish, NS: Author.
Dyck, Lesley
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The proximate determinants of fertility and birth intervals in Egypt [PDF]
In this paper we use calendar data from the 2000 Egyptian Demographic and Health Survey (DHS) to assess the determinants of birth interval length among women who are in union. We make use of the well-known model of the proximate determinants of fertility,
Andrew Hinde, Angela Baschieri
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Determinants of economic growth: will data tell? [PDF]
Many factors inhibiting and facilitating economic growth have been suggested. Will international income data tell which matter when all are treated symmetrically a priori?
Ciccone, Antonio, Jarociński, Marek
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