Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Micro-Market Determinants of Neighborhood Center Rental Rate [PDF]
This investigation expands the limited empirical research on retail rental rates by investigating the determinants of neighborhood shopping center rents.
Marvin L. Wolverton +1 more
core
Implementation mapping to develop strategies for skin-to-skin care in the pediatric cardiac intensive care unit: planning for a hybrid trial. [PDF]
Bettencourt A +7 more
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Determinants of corruption in developing countries [PDF]
Corruption is not a new phenomenon; we are living with it since the birth of government's institutions. Corruption has two dimensions; public sector corruption and private sector corruption. The public sector corruption means, misuse of public office for
Shabbir, Ghulam, Chaudhry, Mumtaz Anwar
core
Use of WHO Growth Standards Rather Than Locally Specific Linear Growth Curves Promotes Equity in Pediatric Growth Research for Children Younger Than 5 Years. [PDF]
Finaret AB, Taylor-Forde P.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Determinants of Diachronic Stability [PDF]
Intro -- The Determinants of Diachronic Stability -- Editorial page -- Title page -- Copyright page -- Table of contents -- Chapter 1. The determinants of diachronic stability -- 1. Setting the scene -- 2. Overview of the volume -- 3.
Farasyn, Melissa. +3 more
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The impact of health literacy on health-related quality of life among individuals with physical disabilities: a path analysis based on the integrated model of health literacy. [PDF]
Kim B, Yoon JY.
europepmc +1 more source

