FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Use of WHO Growth Standards Rather Than Locally Specific Linear Growth Curves Promotes Equity in Pediatric Growth Research for Children Younger Than 5 Years. [PDF]
Nutr RevFinaret AB, Taylor-Forde P.
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The impact of health literacy on health-related quality of life among individuals with physical disabilities: a path analysis based on the integrated model of health literacy. [PDF]
Qual Life ResKim B, Yoon JY.
europepmc +1 more source
Micro-Market Determinants of Neighborhood Center Rental Rate [PDF]
This investigation expands the limited empirical research on retail rental rates by investigating the determinants of neighborhood shopping center rents.
Marvin L. Wolverton +1 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Refining implementation determinants and strategies to scale an electronic assessment option for coordinating family-centred care in early intervention. [PDF]
BMJ Paediatr OpenBosak DL +4 more
europepmc +1 more source
Determinants of corruption in developing countries [PDF]
Corruption is not a new phenomenon; we are living with it since the birth of government's institutions. Corruption has two dimensions; public sector corruption and private sector corruption. The public sector corruption means, misuse of public office for
Shabbir, Ghulam, Chaudhry, Mumtaz Anwar
core