Results 161 to 170 of about 1,258,758 (309)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A Re-Examination of the Role of Foreign Direct Investment and Exports in Malaysia’s Economic Growth: A Time Series Analysis, 1970-2006

International Journal of Management Studies, 2008
The main objective of this study was to re-examine the role of foreign direct investment (FDI) and exports in Malaysia’s economic growth over the period of 1970 to 2006.
Tang Chor Foon
doaj  

Genetic determinants of growth hormone and GH-related phenotypes. [PDF]

BMC Genomics, 2017
Hallengren E, Almgren P, Svensson M, Gallo W, Engström G, Persson M, Melander O.   +6 more
europepmc   +1 more source

Robust Determinants of Income Growth in the Philippines [PDF]

This paper studies the relationship between population dynamics and income growth in the Philippines using data from 74 provinces for the period 1985-2003.
Balisacan, Arsenio M., Briones, Kristine Joy S., Mapa, Dennis S.   +2 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Socioeconomic determinants of growth in a longitudinal study in Nepal. [PDF]

Matern Child Nutr, 2018
Devakumar D, Kular D, Shrestha BP, Grijalva-Eternod C, Daniel RM, Saville NM, Manandhar DS, Costello A, Osrin D, Wells JCK.   +9 more
europepmc   +1 more source

The Effects of Life Expectancy on Fiji's Output: A Time Series Approach from 1970 to 2002 [PDF]

Compared to several cross-country studies on the determinants of growth, time series approaches are relatively few and limited in scope. However, time series studies are useful for country-specific policies.
B Bhaskara Rao, Biman C Prasad, Fozia Nisha   +2 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Structure of the human myostatin precursor and determinants of growth factor latency. [PDF]

EMBO J, 2018
Cotton TR, Fischer G, Wang X, McCoy JC, Czepnik M, Thompson TB, Hyvönen M.   +6 more
europepmc   +1 more source

In Search of the Holy Grail: How to Achieve Pro-Poor Growth? [PDF]

Pro Poor Growth has become a central concern to achieve sustainable poverty reduction in developing countries. Despite being widely used, the term is not well-defined nor has there been a clear policy document that would summarize the determinants and ...
Stephan Klasen
core