Results 51 to 60 of about 1,765,512 (247)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Peut-on différencier l’opération de parcours ?

open access: yesCorela, 2006
The operation named “scanning” (“parcours”) within the framework of the Théorie des Opérations Enonciatives is disseminated among other operations and does not seem to correspond to one particular linguistic marker or even to one homogeneous set of ...
Gérard Mélis
doaj   +1 more source

Defining Determinism [PDF]

open access: yesThe British Journal for the Philosophy of Science, 2018
The article puts forward a branching - style framework for the analysis of determinism and indeterminism of scientific theories, starting from the core idea that an indeterministic system is one whose present allows for more than one alternative possible future. We describe how a definition of determinism stated in terms of branching models supplements
Müller, Thomas, Placek, Tomasz
openaire   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

About the Consept of Pedagogic Paradigm

open access: yesОбразование и наука, 2015
The paradigm concept, essential for comprehension and analysis of the science history, is used quite freely and easily in educational sphere nowadays when some authors discuss their views, theories and developments referring to a new paradigm ...
V. A. Testov
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

The effect of a training program for family caregivers on supportive and obstructive behaviors of families with type 2 diabetes

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Family behaviors are of great importance in the case of chronic diseases that require constant self-management. Chronic diseases management often involves changes in daily procedures that occur in family settings.
Effat Dastigerdi   +4 more
doaj  

Quantitative determination of pefloxacin mesylate by residual-base neutralisation method [PDF]

open access: yesJournal of the Serbian Chemical Society, 2004
This work describes two procedures based on residual base determination for the quantification of pefloxacin mesylate (PFM) in bulk drug and in pharmaceutical products.
HULIKALCHANDRA SHEKAR PRAMEELA   +1 more
doaj  

Determination of Self-Development in the Vocational Educational Environment

open access: yesОбразование и наука, 2015
The paper explores the concept of vocational educational environment combining vocational training, professional development and professional world. The research is aimed at the self-determination analysis of an individual in the above environment.
E. F. Zeer, I. V. Meshkova
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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