HySimODE: a hybrid stochastic-deterministic simulation framework for multiscale models of biological systems. [PDF]
Zamora-Chimal CG, Darlington APS.
europepmc +1 more source
Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
A simple model captures key characteristics of biological non-deterministic genotype-phenotype maps. [PDF]
Martin NS.
europepmc +1 more source
Nano Carbon‐mesh with Excellent Bonding Performance via Hydro‐cage De‐shielding Strategy
A hydro‐cage de‐shielding strategy transforms cellulose‐based films into a dragonfly‐wing‐like nano carbon‐mesh (NCM) adhesive through instantaneous carbonization‐polymerization. The resulting NCM‐plywood achieves exceptional wet shear strength (1.24 MPa at 63°C), exceeding Class II plywood standards, and retains 0.73 MPa after boiling‐water cycles ...
Weijia Yang +14 more
wiley +1 more source
Uncertainty estimation and probabilistic skull shape reconstruction using bayesian neural networks. [PDF]
Li J, Sengupta A, Zachow S.
europepmc +1 more source
The human brain's imagination, which enables autonomous driving hazard avoidance by completing missing visual information, relies on Gaussian‐stochastic neuron. We report the altermagnetic RuO2 spintronic neurons integrating field‐free switching and intrinsic Gaussian stochasticity, building an all‐spin ANN for high‐quality image repairing and high ...
Junwei Zeng +9 more
wiley +1 more source
ArchesWeatherGen: Skillful and compute-efficient probabilistic weather forecasting with machine learning. [PDF]
Couairon G +4 more
europepmc +1 more source
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren +5 more
wiley +1 more source
Geometry‐Controlled Assembly of Self‐Standing Nanorods With Undisturbed Plasmonics
This study reports a geometry‐driven assembly strategy to vertically align Au@Ag core–shell nanorods on PS beads. This well‐defined architecture enables the preservation of the intrinsic optical response of individual nanorods. Thus, demonstrate a highly reproducible SERS enhancement with exceptional uniformity.
Yoel Negrin‐Montecelo +5 more
wiley +1 more source

