Results 161 to 170 of about 98,478 (267)

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Topics and Insights on 1-D Tension Stiffening of an RC Member. [PDF]

Materials (Basel)
Yankelevsky DZ, Karinski YS, Tsemakh D, Feldgun VR.   +3 more
europepmc   +1 more source

Biointegrated Multilayer Stretchable OLED Platform With Strain‐Decoupled Architecture for Durable Phototherapeutic Applications

Advanced Science, EarlyView.
A multilayer stretchable organic light‐emitting diode (SOLED) patch enables conformal, high‐fill‐factor phototherapeutic illumination through vertically decoupled electrodes and robust encapsulation. The textile‐based SOLED platform delivers stable skin‐contact red light for wearable phototherapy and 5‐aminolevulinic acid (ALA)‐mediated photodynamic ...
Young Hyun Son, Myeongheon Lee, Jun‐Yeop Song, Hyo‐Jung Kwon, Kyung Cheol Choi, Jeong Hyun Kwon   +5 more
wiley   +1 more source

Chaotic and complex dynamics expose the limits of counterfactual reasoning. [PDF]

Sci Rep
Aalaila Y, Großmann G, Mukherjee S, Wahl J, Vollmer S.   +4 more
europepmc   +1 more source

Growth‐Pathway‐Controlled van der Waals Epitaxy of Phase‐Selective Tin Sulfides

Advanced Science, EarlyView.
Growth‐pathway‐controlled van der Waals epitaxy enables deterministic phase selection and strain engineering in tin sulfide/WSe2 heterostructures. Direct growth of SnS induces substrate‐mediated strain and phase evolution, whereas sequential growth through an SnS2 buffer suppresses strain transfer and stabilizes pristine α‐SnS, revealing a versatile ...
Jaehyeok Lee, Jinwoo Kim, Gwan‐Hyoung Lee   +2 more
wiley   +1 more source

Material Variability and Quality Control Effects on Shear Resistance of RC Structures: A Reliability Sensitivity Study. [PDF]

Materials (Basel)
Faghfouri S, Strauss A.
europepmc   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Lineage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors. [PDF]

Elife
Salvidge W, Brimson C, Gruenheit N, Huang LY, Pears C, Wolf J, Thompson C.   +6 more
europepmc   +1 more source

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

Advanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng, Qi Yang, Jinze Li, Fuqiang Ma, Xuefeng Wang, Zhen Guo, Chuanyu Li, Dongshu Li, Jia Yao, Zhiqi Zhang, Wei Zhang, Lianqun Zhou   +11 more
wiley   +1 more source