Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen +6 more
wiley +1 more source
A hybrid framework for compartmental models enabling simulation-based inference. [PDF]
Germano DPJ +5 more
europepmc +1 more source
Nano Carbon‐mesh with Excellent Bonding Performance via Hydro‐cage De‐shielding Strategy
A hydro‐cage de‐shielding strategy transforms cellulose‐based films into a dragonfly‐wing‐like nano carbon‐mesh (NCM) adhesive through instantaneous carbonization‐polymerization. The resulting NCM‐plywood achieves exceptional wet shear strength (1.24 MPa at 63°C), exceeding Class II plywood standards, and retains 0.73 MPa after boiling‐water cycles ...
Weijia Yang +14 more
wiley +1 more source
A reproducible EEG-ERP methodology for assessing cognitive decline: integrating P300 latency and resting-state EEG frequency. [PDF]
Derkowski W, Derkowski P.
europepmc +1 more source
The human brain's imagination, which enables autonomous driving hazard avoidance by completing missing visual information, relies on Gaussian‐stochastic neuron. We report the altermagnetic RuO2 spintronic neurons integrating field‐free switching and intrinsic Gaussian stochasticity, building an all‐spin ANN for high‐quality image repairing and high ...
Junwei Zeng +9 more
wiley +1 more source
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
Nonlinear effects of noise on outbreaks of mosquito-borne diseases. [PDF]
Dahlin KJ, Ebey K, Vinson JE, Drake JM.
europepmc +1 more source
Origami‐Mediated Low‐Voltage Electret Soft Robotic Actuators for Human‐Machine Haptic Interfaces
This work introduces an origami‐mediated soft electret actuator that combines compliant mechanical design and enhanced charge retention for low‐voltage vibrotactile feedback. The device delivers reliable tactile cues, demonstrates durable performance under continuous actuation, and enables intuitive interaction in applications such as tactile ...
Han Chen +8 more
wiley +1 more source
Separating random and deterministic sources of computational noise in explore-exploit decisions. [PDF]
Wang S, Wilson RC.
europepmc +1 more source
A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren +5 more
wiley +1 more source

