Results 251 to 260 of about 27,265 (285)

Research progress of DUB enzyme in breast cancer. [PDF]

Clin Exp Med
Tang W, Li N, Lai J.
europepmc   +1 more source

USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression. [PDF]

Cell Death Dis
Haowei Z, Li X, Liao W, Qin X, Jiang Y, Yang H, Zeng H, Li Y, Xie W, Zhang Y, Xu N.   +10 more
europepmc   +1 more source

Insulin resistance and exercise-induced insulin sensitization in skeletal muscle: Insights from personalized phosphoproteomics. [PDF]

J Diabetes Investig
Masuda S, Matsuzaka T.
europepmc   +1 more source

Regulation of the cell cycle and centrosome biology by deubiquitylases. [PDF]

Coulson, JM, Darling, S, Fielding, AB, Prior, IP, Sabat-Pospiech, D   +4 more
core  

Deubiquitinating enzymes: Key regulators of ferroptosis and pyroptosis and novel targets for cancer intervention. [PDF]

Int J Biol Sci
Hsu SK, Kuo IY, Lin PY, Chou CK, Ko CC, Chang WT, Chiu CC.   +6 more
europepmc   +1 more source

WSB1 promotes prostate cancer malignancy through OTUD4-mediated ISOC2 stabilization and P16INK4a suppression. [PDF]

Am J Cancer Res
Sun J, Wang F, Feng Y, Qiu X, Qu W, He X, Xie J, Li G.   +7 more
europepmc   +1 more source

A new sUSPect in T-ALL risk stratification. [PDF]

Blood Adv
Si Lim SJ, Teachey DT.
europepmc   +1 more source

USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK.

Journal of the American Chemical Society
Deubiquitinase-targeting chimeras (DUBTACs) have been recently developed to stabilize proteins of interest, which is in contrast to targeted protein degradation (TPD) approaches that degrade disease-causing proteins.
Jing Liu, Xiaoping Hu, Kaixiu Luo, Yan Xiong, Li Chen, Zhen Wang, Hiroyuki Inuzuka, Chao Qian, Xufen Yu, Ling Xie, Adil Muneer, Dingpeng Zhang, Joao A. Paulo, Xian Chen, Jian Jin, Wenyi Wei   +15 more
semanticscholar   +3 more sources

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Deubiquitinases in cancer

Nature Reviews Cancer, 2023
Ubiquitination is an essential regulator of most, if not all, signalling pathways, and defects in cellular signalling are central to cancer initiation, progression and, eventually, metastasis. The attachment of ubiquitin signals by E3 ubiquitin ligases is directly opposed by the action of approximately 100 deubiquitinating enzymes (DUBs) in humans ...
Grant Dewson, Pieter J. A. Eichhorn, David Komander   +2 more
openaire   +2 more sources