Results 171 to 180 of about 276,793 (392)
Some Effects of Deuterium Oxide on the Quinone Hill Reaction of Chlorella pyrenoidosa Chick. [PDF]
Leonard Horwitz
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One‐pot preparation of various polysubstituted indole derivatives through the highly regioselective hydrohydrazination of various N‐phenylhydrazines with aromatic and aliphatic alkynes by using indium bromide as a sole promotor. The indium‐based promotor showed relatively high tolerance toward various functional groups in a series hydrohydrazination ...
Norio Sakai+2 more
wiley +1 more source
We present the first general synthetic strategy for accessing N(CF3)(CF2H) amines, which display a 2000‐fold increase in stability over N‐CF3 amines. The compounds are synthesized through a desulfurization–fluorination of N‐CF3 thioformamides. Abstract With poor metabolic stability being a major cause of failure in drug development, there is a pressing
Gina Wycich+3 more
wiley +2 more sources
15. Detection of the spectral line of deuterium from the centre of the Galaxy on the wave-length of 91·6 cm. [PDF]
G. G. Getmanzev+2 more
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Ir‐catalyzed sulfur‐directed C─H alkenylation of alkynoates proceeded by using aryl methallyl sulfides. When DMAD was employed, 1,3‐dienes were initially formed and subsequently underwent thermal 1,5‐sigmatropic rearrangement to yield secondary products with high stereoselectivitiy.
Takanori Shibata, Haru Marumo
wiley +1 more source
An attempt to detect the 327-Mc/s line of galactic deuterium [PDF]
R. L. Adgie
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(Z)‐2‐oxazolines are available in a stereoselective fashion by cyclization of propargylic amides with internal triple bonds in the presence of HCl generated in situ from hexafluoroisopropanol (HFIP) and TMSCl. Response surface methodology was crucial to optimize the reaction conditions.
Nicholas Jankowski, Norbert Krause
wiley +1 more source
Beyond Structure: Methylation Fine‐Tunes Stability and Folding Kinetics of bcl2Mid G‐Quadruplex
The introduction of a single 5‐methylcytosine into a G‐rich sequence originating from the B‐cell lymphoma 2 (BCL2) gene promoter affects both the folding kinetics and thermodynamics of the two G4 structures and thus plays a crucial role in regulating G4 folding pathways, which has significant implications for the control of gene expression.
Nataša Medved+5 more
wiley +2 more sources
Synthesis of Benzodithieno[5.5.5.6]fenestranes: Unexpected Epimerization and Regiochemical Outcomes
Isomeric [5.5.5.6]fenestranes bearing one benzene and two thiophene rings annulated to all‐cis‐ and cis,cis,trans,cis‐fenestrane cores are presented. The synthesis route previously established for the corresponding tribenzo[5.5.5.6]fenestranes includes twofold cyclodehydration of the stereoisomeric spiro[cyclohexane‐1,2’‐indane]‐1',3'‐diol ...
Dietmar Kuck+5 more
wiley +1 more source
Comment on "A centroid molecular dynamics study of liquid para hydrogen and ortho deuterium" [J. Chem. Phys. 121, 6412 (2004)] [PDF]
We show that the two phase points considered in the recent simulations of liquid para hydrogen by Hone and Voth lie in the liquid-vapor coexistence region of a purely classical molecular dynamics simulation.
Konieczny, Martin+4 more
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