Results 211 to 220 of about 104,664 (293)

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Structural insights into antibody-antibody interactions in sandwich ELISA: implications for assay development and performance. [PDF]

Anal Bioanal Chem
Su Y, Zhao B, Moon Y, Fu Y, Karayusuf E, Ressegue E, Xue X, Zylstra J, Grimaldi C, Zhang B, Xiao H, Li N.   +11 more
europepmc   +1 more source

Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao, Edvaldo Vasconcelos Soares Maciel, Frederik Lermyte, Owen S. Skinner   +3 more
wiley   +1 more source

Identification of a key water molecule involved in the macrophage migration inhibitory factor-catalyzed tautomerization of para-hydroxyphenylpyruvate using neutron crystallography. [PDF]

Protein Sci
Schröder GC, Crichlow GV, Jablonowski E, Pantouris G, Nix J, Chayen N, Meilleur F, Lolis EJ.   +7 more
europepmc   +1 more source

Influence of THF as Internal‐Donor on Ziegler‐Natta Polyethylene Catalysts

Macromolecular Reaction Engineering, EarlyView.
Ziegler–Natta catalysts remain widely applied due to robustness, handling ease, and cost‐effectiveness. To support further optimization, we examine how internal donors such as tetrahydrofuran influence catalyst performance and polymer characteristics.
Alexander Mottl, Sarah Brunner, Patrik Schneider, Fabian Hofmann, Moritz Pischulti, Dario Pindirc, Clemens Schwarzinger, Christian Paulik   +7 more
wiley   +1 more source

Magnesium as a conformational gatekeeper of KRAS: Structural dynamics and therapeutic implications. [PDF]

Protein Sci
Srinivasu BY, Damerla TS, Stec A, Zhou Z, Engen JR, Westover KD, Wales TE.   +6 more
europepmc   +1 more source

In Vivo Dynamic D2O‐MRI for Quantifying Apparent CSF Water Renewal Across Ventricular and Extraventricular Compartments

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose The choroid plexus has long been regarded as the principal source of cerebrospinal fluid (CSF), yet this view remains unresolved. We developed a dynamic indirect D2O MRI approach to quantify regional apparent CSF water renewal in vivo in rats at 9.4 T.
Zhao Zhang, Yun Wu, Yanmin Zheng, Zhuoyang Lin, Ye Li, Qiong Ye   +5 more
wiley   +1 more source

Controlled Deuteration of Phosphatidylcholine Biosynthetically Produced from Engineered <i>Escherichia coli</i> for SANS Studies. [PDF]

ACS Omega
Zhang Q, Keller MJ, Leite W, Hettich RL, O'Neill H, Zhang HH.   +5 more
europepmc   +1 more source

Copolymer Synthesis of N‐Vinylacetamide and 2‐Methylene‐1,3‐Dioxepane Provides a New Degradable Polymer

Journal of Polymer Science, Volume 63, Issue 6, Page 1306-1318, 15 March 2025.
ABSTRACT N‐vinylamides, especially noncyclic N‐vinylacetamide (NVA), have been used in various applications such as biomaterials, surfactants, and hydrogels. However, their potential to copolymerize with cyclic ketene acetal (CKA) to create degradable polymers is underexplored.
Mukmin Sapto Pamungkas, Tsuyoshi Ando, Hiroharu Ajiro   +2 more
wiley   +1 more source

Small Molecule Stabilization of Diverse Amyloidogenic Immunoglobulin Light Chains Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. [PDF]

J Mol Biol
Peterle D, Yan NL, Klimtchuk ES, Srinivasu BY, Brusic V, Rhoades D, Wales TE, Gursky O, Kelly JW, Kelly JW, Engen JR, Morgan GJ.   +11 more
europepmc   +1 more source