Results 221 to 230 of about 104,664 (293)

Information‐Theoretic Framework for Allosteric Communication Pathway Prediction From Protein Structure

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Allosteric communication is fundamental to the function of proteins, but identifying the residue‐level pathways through which signals travel and their directionality is still a major challenge. Here we present a multi‐metric information‐theoretic framework that identifies candidate allosteric communication pathways from a single protein ...
Aysima Hacisuleyman, Dirk Fasshauer
wiley   +1 more source

Deuterated Radical Emitters Achieve 10.8% EQE at 800 nm with Remarkably Enhanced Operational Stability. [PDF]

Nat Commun
Wang SF, Kung YC, Wu CC, Huang PY, Su ZH, Chuang WT, Hung WY, Chou PT.   +7 more
europepmc   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source

Pd-Catalyzed Transfer Hydrogenation of Alkenes Using Tetrahydroxydiboron as the Sole Hydrogen Donor

SynOpen
Mahshid Yaghoubi, Isabella C. Reyes, Benjamin J. Stokes   +2 more
doaj   +1 more source

Hydrogen Removal from Fe at Room Temperature: A Study on Hydrogen Trapping Mechanisms. [PDF]

Materials (Basel)
Zhang K, Li H, Guan D.
europepmc   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Application of mass spectrometry techniques for analysis of higher order structure of proteins.

Analyst
Herath D, Walls KN, Dollar AN, Webb IK.
europepmc   +1 more source

Allosteric inhibition of human mitochondrial ClpP by hijacking the dordaviprone (ONC201) binding site. [PDF]

Nat Commun
Goncalves MM, Uday AB, Watson IDG, Chau AM, Kalhor-Monfared S, Wan B, Kiyota T, Currie SQW, Jitkova Y, Feng Y, Diamandas M, Ling D, Ma M, Mancini RS, Wang Z, Casás-Selves M, Joshi D, Mohammed M, Subramaniam R, Fernandes EL, Yan Y, Pomroy N, Hurren R, Gronda M, Velyvis A, Yudin AK, Reed MA, Prive G, Aman A, Isaac M, Marcellus R, Uehling D, Schimmer AD, Zeytuni N, Vahidi S.   +34 more
europepmc   +1 more source

Mixed TiO2–SiO2 thin coatings for selective adsorption and sunlight‐powered photodegradation of cationic pollutants

Responsive Materials, EarlyView.
Environmental pollution and water scarcity demand innovative purification methods. This study presents a sol‐gel approach to fabricate mixed silica–titania thin films joining photocatalytic activity with selective sorption capability. The films exhibit higher surface area, enhanced degradation of cationic and improved performance over bare titania ...
Andrea Lanfranchi, Simone Bertucci, Margherita Peragallo, Fabiano Martorelli, Giovanni Manfredi, Davide Avanzino, Roberto Spotorno, Stefano Alberti, Davide Comoretto, Francesco Di Stasio, Maddalena Patrini, Federico Locardi, Mirko Prato, Paola Lova   +13 more
wiley   +1 more source

Nuclear-Electronic Orbital General Rate Theory: Predicting Hydrogen Kinetic Isotope Effects in the Deep Tunneling Regime. [PDF]

J Chem Theory Comput
Paenurk E, Yoo JM, Hammes-Schiffer S.
europepmc   +1 more source