A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee +9 more
wiley +1 more source
Mechanism of beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy. [PDF]
Pakharukova N +15 more
europepmc +1 more source
Selective Photoinduced α‐Amino C(sp3)–H Alkylation Mediated by NHC–Borane
Herein, we report a selective photoinduced functionalization of α‐amino C(sp3)─H bonds mediated by NHC–boranes. This reaction proceeds efficiently without the need for any external radical initiator or photoredox catalyst. Mechanistic studies reveal that the reaction proceeds via an efficient radical chain, featuring the formation of an aryl radical ...
Gabin Lalande +2 more
wiley +1 more source
Postprandial Vitamin E Plasma Enrichment and Second Meal Effect in Women with and without Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]
Violet PC +10 more
europepmc +1 more source
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu +7 more
wiley +1 more source
Reprogramming NAD(P)<sup>+</sup>-Binding Proteins for Iminium Biocatalysis via a Synthetic NAD<sup>+</sup>-Type Cofactor. [PDF]
Wang S +5 more
europepmc +1 more source
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning +7 more
wiley +1 more source
Characterization of a Heme-Binding Radical SAM Enzyme HemW from <i>Moraxella catarrhalis</i>. [PDF]
Padgett CM +6 more
europepmc +1 more source
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi +5 more
wiley +1 more source
A ligand-controlled regiodivergent three-component Heck-Tsuji reaction utilizing umpolung hydrazones enabled by palladium catalysis. [PDF]
Chen EFW +4 more
europepmc +1 more source

