Results 181 to 190 of about 572,691 (264)

Unanticipated enhancement of phosphide nucleophilicity in dimethyl sulfoxide for advanced catalytic P-C bond formation reactions. [PDF]

Chem Sci
Finfer EJ, Jheng NY, Moniruzzaman M, Akom MD, Waterman R.   +4 more
europepmc   +1 more source

Deprotective Alkylation: A Platform for Alcohol‐to‐Amine Interconversion Using Nonafluoromesitylenesulfonamides

Angewandte Chemie International Edition, Volume 65, Issue 43, 19 October 2026.
The straightforward conversion of alcohols to tertiary or secondary amines employing Nms‐amides in a single operation is described. The transformation features broad functional group tolerance and high stereospecificity, underscoring its utility in the synthesis of isotope‐labeled pharmaceuticals.
Jakub Brześkiewicz, Kunj Kapur, Boris Maryasin, Nuno Maulide   +3 more
wiley   +1 more source

Characterization of Full‐Length Antibody Complexes Through HDX‐Mass Spectrometry Coupled With NMR Spectroscopy: New Insight Into Avelumab/PD‐L1 Interaction

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Combining HDX‐MS and NMR enables the mapping of epitopes and paratopes in full‐length antibody complexes, revealing transient interactions and potential artifacts. ABSTRACT Recombinant biomacromolecules have significantly transformed pharmaceuticals, in particular monoclonal antibodies (mAbs) that target key areas in oncology, immunology, inflammation,
Francesca Sacco, Fabio Baroni, Angela Capolupo, Sofia Petrocchi, Jonathan Zöller, Linda Cerofolini, Pasquale Russomanno, Rebecca Calamandrei, Bianca Susini, Siyu Lin, Fabio D'Amici, Enrico Ravera, Julian Langer, Marco Fragai   +13 more
wiley   +2 more sources

A Portable UV-LED Dual-Nafion Microfluidic Platform for Label-Free Trace Protein Preconcentration and Absorbance Detection. [PDF]

Biosensors (Basel)
Shih YJ, Chen YS, Jen CP.
europepmc   +1 more source

Differential Impacts of Proxy Archives on Paleoclimate Reconstruction Performance

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 19, 16 October 2026.
Abstract Reconstructing past climates is challenging because pre‐instrumental observations are geographically sparse and proxy records are noisy; data assimilation offers one approach to address these limitations. Although such reconstructions are now widespread, the extent to which different proxy archives determine their accuracy remains unclear.
Patrick G. Cho, Feng Zhu, Diogo Bolster, Marc F. Müller   +3 more
wiley   +1 more source

Heavy water labeling reveals metabolic flexibility of amino acid and polyamine pathways in mammalian cells. [PDF]

Commun Chem
Gonzalez-Ibarra A, Arroyo-Negrete M, Banaszuk-Krupa W, Socała K, Gapińska N, Wlaź P, Torres-Elguera JC, Sawoszczuk T, Tchórzewski M, Hatzoglou M, Krokowski D.   +10 more
europepmc   +1 more source

Proton‐Coupled Electron Transfer in Reaction of Catecholamines: Experimental and Computational Approach

ChemPhysChem, Volume 27, Issue 19, 14 October 2026.
Experimentally determined rate constants, kinetic isotope effects, and thermodynamic activation parameters in a nonpolar solvent, as well as density functional theory computational analysis of intrinsic bond orbitals (IBOs) along the intrinsic reaction coordinate (IRC) path including the transition state (TS), suggest that hydrogen transfer from ...
Ana Karković Marković, Mia Jovanić, Dijana Kolezarić, Viktor Pilepić   +3 more
wiley   +1 more source

Two-year daily precipitation stable isotope dataset (δ¹⁸O and δ²H) from a continental station in NW Croatia. [PDF]

Data Brief
Briški M, Palatinuš I, Bajo P, Brčić V.   +3 more
europepmc   +1 more source

Structural insights into antibody-antibody interactions in sandwich ELISA: implications for assay development and performance. [PDF]

Anal Bioanal Chem
Su Y, Zhao B, Moon Y, Fu Y, Karayusuf E, Ressegue E, Xue X, Zylstra J, Grimaldi C, Zhang B, Xiao H, Li N.   +11 more
europepmc   +1 more source