Results 161 to 170 of about 549,888 (271)

Hyperpolarized MRI in Oncology—A Review of Clinical Studies and Evaluation of Preclinical Liver Studies

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Hyperpolarized MRI is a promising clinical imaging modality in oncology, offering at least nine imaging contrasts obtainable with hyperpolarized [1‐13C]pyruvate as the injected agent, depending on the tissue and condition under investigation. Preclinical studies suggest that hyperpolarized MRI is warranted for detecting hepatocellular carcinoma within ...
Naama Lev‐Cohain, Jacob Sosna, Rachel Katz‐Brull   +2 more
wiley   +1 more source

Unanticipated enhancement of phosphide nucleophilicity in dimethyl sulfoxide for advanced catalytic P-C bond formation reactions. [PDF]

Chem Sci
Finfer EJ, Jheng NY, Moniruzzaman M, Akom MD, Waterman R.   +4 more
europepmc   +1 more source

Function within disorder: Small heat shock proteins use different functional regions to chaperone tau aggregation

Protein Science, Volume 35, Issue 10, October 2026.
Abstract In numerous neurodegenerative diseases known collectively as tauopathies, the microtubule‐associated protein tau forms fibrillar aggregates that are hallmarks of disease pathology. Tauopathies represent a substantial fraction of diseases associated with protein misfolding.
Mia Cervantes, Maria K. Janowska, Lisa M. Tuttle, Miklos Guttman, Abhinav Nath, Rachel E. Klevit   +5 more
wiley   +1 more source

Exclusive Hydroformylation of Terminal Olefins: A Phosphorus‐Free Ruthenium System for the Selective Functionalization of Complex Mixtures

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Development of a phosphorus‐free Ru/DBU catalyst enabling highly chemo‐ and regioselective hydroformylation of terminal olefins, sparing internal double bonds. Optimization of reaction parameters, ligand effects, and substrate scope including industrial feedstocks was realized.
Mohamed Niyaz Vellala Syed Ali, Ida Ziccarelli, Dilver Peña Fuentes, Christoph Kubis, Robert Franke, Ralf Jackstell, Matthias Beller   +6 more
wiley   +2 more sources

Heavy water labeling reveals metabolic flexibility of amino acid and polyamine pathways in mammalian cells. [PDF]

Commun Chem
Gonzalez-Ibarra A, Arroyo-Negrete M, Banaszuk-Krupa W, Socała K, Gapińska N, Wlaź P, Torres-Elguera JC, Sawoszczuk T, Tchórzewski M, Hatzoglou M, Krokowski D.   +10 more
europepmc   +1 more source

Determinants of Abl kinase stability and drug binding thermodynamics: Role of regulatory domains and phosphorylation

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Activity dysregulation of Abl kinase is the primary cause for chronic myeloid leukemia (CML). Despite extensive characterization, the thermodynamic basis of Abl stability and inhibitor recognition remains incompletely understood. To characterize the cooperative folding organization of Abl and the communication between its structural units, we ...
Alan Juárez‐Barragán, J. Alberto Escobar‐Cázares, Miguel A. Medina‐Gómez, Ileana Tobías‐Juárez, Axel Luviano, Enrique García‐Hernández   +5 more
wiley   +1 more source

Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Non‐covalent co‐assembly of BTA with antiviral surfactants produces ratio‐dependent morphologies. Fibrous supramolecular polymers exhibit superior HSV‐1 inhibition, revealing multivalent fiber‐virus interactions and highlighting supramolecular co‐assemblies as a powerful strategy for functional biomedical nanomaterials with demonstrated tunable ...
Christian Zoister, Boris Schade, Paulina Sittinger, Xianwen Lou, Esmee de Korver, Freek V. de Graaf, Ranen Etouki, Chuanxiong Nie, Kai Licha, Kai Ludwig, Abhishek Kumar Singh, E. W. Meijer, Rainer Haag   +12 more
wiley   +2 more sources

Two-year daily precipitation stable isotope dataset (δ¹⁸O and δ²H) from a continental station in NW Croatia. [PDF]

Data Brief
Briški M, Palatinuš I, Bajo P, Brčić V.   +3 more
europepmc   +1 more source

Evasins: Biology and Therapeutic Potential of Broad‐Spectrum Chemokine Inhibitors

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Emilia L. Bialek, Roos Buds, Ingrid Dijkgraaf, Pedro E. Marques   +3 more
wiley   +1 more source

Enhanced nuclear fusion in the sub-keV energy regime. [PDF]

Nat Commun
Karahadian ME, Colborne M, Persaud A, Schenkel T, Munday JN.   +4 more
europepmc   +1 more source