Results 161 to 170 of about 572,691 (264)

An Investigation Into the Yields of 3,4‐Methylenedioxyphenyl‐2‐propanone (MDP2P) From Glycidate Pre‐Precursors

Drug Testing and Analysis, Volume 18, Issue 11, Page 1470-1479, November 2026.
Hydrolysis of the glycidate pre‐precursors MMDMG and EMDMG was evaluated for MDP2P production. Acid hydrolysis of MMDMG (HCl, 100°C, 18 h) yielded the highest MDP2P recovery (79%), whereas base hydrolysis produced only slightly lower yields (73%), demonstrating both pathways are effective routes to this key MDMA precursor.
Alexandra L. Mercieca, Ella S. Schuett, Andrew M. McDonagh, Shanlin Fu, Morgan Alonzo   +4 more
wiley   +1 more source

HDX-MS-Guided computational modeling for rapid and accurate antibody-antigen interface mapping. [PDF]

MAbs
McMahon W, Zhang H, Li X, Oganesyan V, Payne S, Mehzabeen N, Dyk NV, Liu W, Howard W, Zhao P, Zhang Y, Fang M, Chen X, Mazor Y, Shi Y.   +14 more
europepmc   +1 more source

Medjool Date Seed Polysaccharides Attenuate DSS‐Induced Colitis and Associated Hepatic Oxidative Injury in Mice, Accompanied by Gut Microbiota Alterations

Food Frontiers, Volume 7, Issue 6, November 2026.
Medjool date seeds were dried, milled, and extracted (80°C, 180 min), followed by centrifugation (1000 rpm, 15 min) and BCA analysis to obtain the polysaccharide fraction (MDSP), which was characterized by TEM, FTIR, XPS, NMR, UV‐Vis, and TGA. In Balb/c mice with DSS‐induced colitis (2.25% DSS, Day 1.15), oral administration of MDSP‐H (300 mg/Kg ...
Sadeeq Ullah, Caixia Guo, Xiao Zou, Junhong Xie, Hidayat Ullah, Muhammad Ishaq, Xiang Xiao, Wenqi Xu, Yanguang Cong, Chuanjiang Dong, Lu Li   +10 more
wiley   +1 more source

Gram-Scale Synthesis of Perdeuterated Paracetamol. [PDF]

J Labelled Comp Radiopharm
Park A, Edkins RM, McCorquodale J, Tellam J, Youngs S, Edkins K.   +5 more
europepmc   +1 more source

A Multi‐Crosslinkable Methacrylated Alginate‐GelMa Bioink for Drop‐on‐Demand Bioprinting

Macromolecular Bioscience, Volume 26, Issue 11, November 2026.
A multi‐crosslinkable methacrylated oxidized alginate–GelMA system enables precise drop‐on‐demand bioprinting by integrating tailored polymer functionality with tunable hydrogel properties. The designed macromolecular network combines photochemical, dynamic covalent, and ionic interactions to achieve printable, cytocompatible bioinks for advanced three‐
Tommi Bui, Emine Karakaya, Jessica Faber, Jonas Röder, Jörg Teßmar, Julian Bauer, Oliver Friedrich, Silvia Budday, Aldo R. Boccaccini, Rainer Detsch   +9 more
wiley   +1 more source

Interaction With Surface Spins as a Contribution to Nuclear Magnetic Relaxation of Liquids Adsorbed in Mesoporous Materials

Magnetic Resonance in Chemistry, Volume 64, Issue 11, Page 917-929, November 2026.
Liquids at silica interfaces experience demixing as a consequence of their respective polarity. The distribution of liquids and their primary relaxation contributions are studied by surface modification with OD and radical moieties, respectively. ABSTRACT NMR relaxation of liquids in the presence of solid interfaces, such as silica gel or porous glass,
Carlos Mattea, Hannah Leptin, Moritz Schmidt, Siegfried Stapf   +3 more
wiley   +1 more source

Stable Isotope Labeling to Track De Novo Fatty Acid Synthesis in Mouse Cartilage-Enriched Joint Tissue In Vivo: A Practical Workflow. [PDF]

J Orthop Res
Moradi S, Binoy A, Zhu S.
europepmc   +1 more source

DreamFold: A World Model to efficiently generate protein folding pathways in the latent space

Protein Science, Volume 35, Issue 11, November 2026.
Abstract While there is an abundance of static data for the structure of biological macromolecules, the data regarding their folding mechanisms and dynamics is scarce, posing a challenge to the training of AI models. The World Model approach, which has been very successful in robotics, can come in handy in this regard. From limited data, it can build a
Alan Ianeselli, Jewon Im, Eddie Cavallin, Mark B. Gerstein   +3 more
wiley   +1 more source

SARS-CoV-2 main protease inhibition through dimerization promotion by peptidomimetic inhibitors and disruption by ebselen. [PDF]

Elife
Liu C, Jia Q, Zhao C, Yao ZP.
europepmc   +1 more source

A generalizable method for the purification and biophysical characterization of bacterial membrane receptors

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Membrane‐embedded bacterial receptors are challenging to express and purify in soluble form, yet their isolated domains are essential tools for structural and ligand‐discovery studies. Pseudomonas aeruginosa relies on the TonB‐dependent heme receptor HasR for iron acquisition, a process central to its pathogenicity.
Federico Bosetto, Maria Zacharopoulou, Mark Bycroft, Monika Kish, Giovanna Zinzalla, Pamela J. E. Rowling, Stephen H. McLaughlin, Jonathan J. Phillips, Laura S. Itzhaki, Ioanna Mela   +9 more
wiley   +1 more source