Results 151 to 160 of about 38,233 (200)
Small, EarlyView.Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira +9 more
wiley +1 more source
Small, EarlyView.IBD is driven by a vicious cycle of dysbiosis, barrier dysfunction, and immune dysregulation. We developed an inulin–butyrate conjugate nanogel (IBN) that accumulates in inflamed colon and releases butyrate via microbial inulinase/esterase. The inulin shell remodels the microbiome, while localized butyrate strengthens barrier integrity and promotes ...
Nayoon Park +7 more
wiley +1 more source
Small, EarlyView.The emerging BaCu2Se2 semiconductor compound is synthesized in combinatorial thin film libraries for fast screening of its fundamental properties related to the application in sustainable energy sources. Ba‐rich and Cu‐rich compositions are explored.
Marin Rusu +16 more
wiley +1 more source
The Chemical Record, EarlyView.Nickel foam—one material, two faces, and several versatile roles depending on electrolytic conditions. For more than 50 years, nickel foam electrodes have served in electrosynthesis as powerful and readily available electrode materials. Due to their inexpensive nature and easy handling, they have been widely employed.
Rok Narobe +2 more
wiley +1 more source
Metabolic thermodynamics: pertinent reference state and energy potentials
The FEBS Journal, EarlyView.A recommendation and method to view the energy potentials of metabolites with reference to (green arrow) a biochemical precursor state (in green: water, Mg2+, phosphate, bicarbonate, ammonium, and sulfate, at pH = 7) rather than (the red arrow) the physical–chemical reference state (in grayish red) that is alien to biology, that is, O2, H2, N2 at 1 ...
Hans V. Westerhoff +21 more
wiley +1 more source
The FEBS Journal, EarlyView.Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna +17 more
wiley +1 more source
The FEBS Journal, EarlyView.Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero +8 more
wiley +1 more source
Obesity Reviews, EarlyView.ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye +6 more
wiley +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng +4 more
wiley +1 more source
Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine
Photochemistry and Photobiology, EarlyView.6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes +6 more
wiley +1 more source