Results 171 to 180 of about 946,755 (288)

Direct Conversion of Aryl Iodides Into Benzylamines by Aminomethylation: Reaction Scope, Mechanistic Studies, and Applications

European Journal of Organic Chemistry, EarlyView.
This study presents an efficient aminomethylation of aryl iodides with formamides for the synthesis of benzylamines using a reusable palladium catalyst at a loading of 65 mol ppm. The substrate scope is systematically evaluated, and mechanistic investigations provide insight into the reaction pathway and the origin of the observed catalytic efficiency.
Abhijit Sen, Atsuya Muranaka, Yu Hatakenaka, Aya Ohno, Yoichi M. A. Yamada   +4 more
wiley   +1 more source

Establishment of the deuterium oxide dilution method as a new possibility for determining the transendothelial water permeability. [PDF]

Pflugers Arch
Müller H, Hahn J, Gierke A, Stark R, Brunner C, Hoffmann TK, Greve J, Wittekindt O, Lochbaum R.   +8 more
europepmc   +1 more source

Selective N‐Functionalization of Pyrazoles

European Journal of Organic Chemistry, EarlyView.
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek, Matthias Schrader, Christopher J. Teskey   +2 more
wiley   +1 more source

Nucleophilic Reactions of Cyclobutenones and the Related 4,4‐Dichlorocyclobutenone Derivatives

European Journal of Organic Chemistry, EarlyView.
Cyclobutenone derivates and their 4,4‐dichloro counterparts have an uninterrupted attention as useful synthons in the synthesis of complex organic molecules. Their nucleophilic reactions remain underexplored. This review brings attention to these reactions, whose outcome is not straightforward.
Sarah J. Wright, Muhluri H. Mthombeni, Songeziwe Ntsimango   +2 more
wiley   +1 more source

Molybdooxaziridine Catalysis: Synthesis of α‐Hydroxysulfones From Styrenes Through an ATRA Process

European Journal of Organic Chemistry, EarlyView.
This work has discovered that molybdooxaziridine catalysts promote the hydroxysulfonation of substituted α‐methyl‐styrenes using N‐Ts‐hydroxylamine as the nitrogen source. An atom‐transfer‐radical‐addition mechanism involving the stepwise addition of Ts and hydroxy radicals takes place.
Alyssa N. Singer, Gustavo Moura‐Letts
wiley   +1 more source

Metabolomic insights for the authentication and traceability of antibiotic‐free pork: a pilot study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Antibiotic‐free production within the meat supply chain is a source of concern since new voluntary label claims need to be authenticated to prevent fraud. Therefore, an untargeted 1H NMR‐based metabolomics approach coupled to unsupervised (principal component analysis) and supervised (orthogonal partial least squares discriminant ...
Maria Olga Varrà, Maria Pia Fabrile, Sergio Ghidini, Augusta Caligiani, Federico Scali, Veronica Lolli, Giovanni Loris Alborali, Adriana Ianieri, Emanuela Zanardi   +8 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Interaction With Surface Spins as a Contribution to Nuclear Magnetic Relaxation of Liquids Adsorbed in Mesoporous Materials

Magnetic Resonance in Chemistry, EarlyView.
Liquids at silica interfaces experience demixing as a consequence of their respective polarity. The distribution of liquids and their primary relaxation contributions are studied by surface modification with OD and radical moieties, respectively. ABSTRACT NMR relaxation of liquids in the presence of solid interfaces, such as silica gel or porous glass,
Carlos Mattea, Hannah Leptin, Moritz Schmidt, Siegfried Stapf   +3 more
wiley   +1 more source

Copolymer Synthesis of N‐Vinylacetamide and 2‐Methylene‐1,3‐Dioxepane Provides a New Degradable Polymer

Journal of Polymer Science, Volume 63, Issue 6, Page 1306-1318, 15 March 2025.
ABSTRACT N‐vinylamides, especially noncyclic N‐vinylacetamide (NVA), have been used in various applications such as biomaterials, surfactants, and hydrogels. However, their potential to copolymerize with cyclic ketene acetal (CKA) to create degradable polymers is underexplored.
Mukmin Sapto Pamungkas, Tsuyoshi Ando, Hiroharu Ajiro   +2 more
wiley   +1 more source