Results 191 to 200 of about 18,004 (298)

On the Origin of the Brain Semi‐Heavy Water Deuterium MR Signal Following Administration of Deuterated Metabolic Substrate: A Cautionary Tale

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate the extent to which the appearance of HOD in the brain following systemic administration of a deuterated substrate is due to local brain metabolism versus body metabolism. Methods [6,6‐2H2]glucose, which is transported across the blood‐brain barrier (BBB), and [6,6‐2H2]fructose (Fruc), which does not cross the BBB, were ...
Joseph J. H. Ackerman, Xia Ge, Nick Rensing, Jeffrey J. Neil, Liu Lin Thio, Joel R. Garbow   +5 more
wiley   +1 more source

Atlas of Brain Glucose Metabolism Using Deuterium Metabolic Imaging at 3 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Deuterium metabolic imaging (DMI) offers noninvasive magnetic resonance imaging (MRI)–based assessment of metabolism in vivo, making it a relevant paraclinical tool for diseases with neurological metabolic alterations. This study aimed to establish a normative reference atlas of brain glucose metabolism accounting for age and sex ...
Kamilla K. Trosborg, Nichlas V. Christensen, Malene Aastrup, Nikolaj Bøgh, Janne K. Mortensen, Hanne Gottrup, Per Borghammer, Mattias H. Kristensen, Esben S. S. Hansen, Sofie H. Christensen, Jack J. Miller, Rolf F. Schulte, Michael Vaeggemose, Lotte B. Bertelsen, Christoffer Laustsen   +14 more
wiley   +1 more source

Copolymer Synthesis of N‐Vinylacetamide and 2‐Methylene‐1,3‐Dioxepane Provides a New Degradable Polymer

Journal of Polymer Science, Volume 63, Issue 6, Page 1306-1318, 15 March 2025.
ABSTRACT N‐vinylamides, especially noncyclic N‐vinylacetamide (NVA), have been used in various applications such as biomaterials, surfactants, and hydrogels. However, their potential to copolymerize with cyclic ketene acetal (CKA) to create degradable polymers is underexplored.
Mukmin Sapto Pamungkas, Tsuyoshi Ando, Hiroharu Ajiro   +2 more
wiley   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

Pest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus, Liina Soonvald, Iris Callewaert, Ana Isabel Silva, Ericmar Ávila Dos Santos, Silva Vilumets, Riina Kaasik, Sven Vereecken, Lenny Van Daele, Peter Dubruel, Jonathan Willow, Clauvis Nji Tizi Taning, Kristof De Schutter, Eve Veromann   +13 more
wiley   +1 more source

Visible-light-mediated deuteration of silanes with deuterium oxide. [PDF]

Chem Sci, 2019
Zhou R, Li J, Cheo HW, Chua R, Zhan G, Hou Z, Wu J.   +6 more
europepmc   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Gelation and luminescence of lanthanide hydrogels formed with deuterium oxide. [PDF]

RSC Adv, 2019
Zama Y, Yanai K, Takeshita J, Ishii A, Yamanaka M, Hasegawa M.   +5 more
europepmc   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

Small, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira, Hiroshi Kamizawa, Yujiro Hamada, Wataru Fushimoto, Hiroshi Y. Yoshikawa, Yuji Higaki, Atsushi Takahara, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura   +9 more
wiley   +1 more source

Cryogenic TDS Platform for Quantitative Hydrogen Isotope (H2/D2/HD) Separation via Quantum Sieving in Porous Materials

Small, EarlyView.
The AC‐TDS enables precise hydrogen isotope analysis over a wide temperature range (15–900 K), allowing both physisorption and chemisorption processes to be investigated under gas exposure conditions. Through calibration, this system achieves reliable quantitative desorption analysis, including direct quantification of H2, D2, and HD under mixed ...
Minji Jung, Hyunlim Kim, Michael Hirscher, Hyunchul Oh   +3 more
wiley   +1 more source

Volatile profiles and involvement step of moisture in bulk oils during oxidation by action of deuterium oxide (D₂O). [PDF]

Food Sci Biotechnol, 2018
Lee CK, Yi BR, Kim SH, Choi HS, Kim MJ, Lee JH.   +5 more
europepmc   +1 more source