Results 181 to 190 of about 24,004 (264)

The protective power of connection: a proposed conceptual model of social supports in the context of youth adversity, disrupted attachment, and trauma symptoms. [PDF]

Front Psychol
Sox DM, Deutsch NL, Jennings PA, Min HH.
europepmc   +1 more source

Enhancing Maturation of Human Neuromuscular Organoids via Electrical Stimulation

Advanced Science, EarlyView.
A framework for on‐demand and non‐invasive exposure of human neuromuscular organoids (NMOs) to electrical stimuli is established to promote their maturation. The robustness and effectiveness of different stimulation regimes are evaluated via thorough characterization of organoid tissue structure and contraction capacity. Chronic electrical stimulation,
Chrysanthi‐Maria Moysidou, Inês Afonso Martins, Ismail Amr El‐Shimy, Iacopo Bicci, Donatella Cea, Christina Bukas, Isra Mekki, Mara‐Camelia Rusu, Aylin Nebol, Ines Lahmann, Marie Piraud, Enrico Klotzsch, Mina Gouti   +12 more
wiley   +1 more source

The CancerenD24: A Novel Blood Test That Can Prevent Colorectal Cancer. [PDF]

Gastro Hep Adv
Shapira S, Yaakobi H, Kazanov D, Motlaq M, Galazan L, Greenshpon R, Bruck H, Deutsch N, Deutsch L, Arber N.   +9 more
europepmc   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Inherited TBX4 frameshifting variants predicted to escape nonsense mediated decay in two families with variable phenotypes, including lethal lung developmental disorders. [PDF]

Hum Genomics
Pande SA, Chan Joiner H, Szafranski P, Gambin T, Wright M, Wang Q, Walters M, Friedman JM, Saunders J, Avdimiretz N, Boerkoel CF, Cortes-Santiago N, Deutsch G, Stankiewicz P.   +13 more
europepmc   +1 more source

Light‐Imprinted Chirality in Nanomaterials: From Principles to Applications

Advanced Science, EarlyView.
Light‐induced chirality represents a transformative paradigm for fabricating chiral nanostructures. This review provides a comprehensive framework encompassing light‐based strategies for imprinting and tuning chirality in nanomaterials, which guides researchers in harnessing light to create next‐generation functional materials.
Xinru Jin, Emiliano Cortés, Alexander O. Govorov, Tao Ding   +3 more
wiley   +1 more source

[Lost in translation-an investigation of listening effort and performance in cochlear implant users in first and foreign language settings]. [PDF]

HNO
Thyson S, Volpert S, Werminghaus M, Althaus L, Klenzner T.   +4 more
europepmc   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Spatial transcriptomics of developing human lungs defines cellular phenotypes associated with age, lineage and location. [PDF]

Sci Rep
Ren Y, Danopoulos S, Deutsch GH, Glass IA, Mariani TJ, Bhattacharya S.   +5 more
europepmc   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source