Results 211 to 220 of about 409,570 (285)

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Fenthion: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

Malathion: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Parathion: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Further Evidences for the Sulfur Spillover on Carbon: Thermodynamic Aspects and Effects on Li‐S Solid‐State Batteries

Advanced Science, EarlyView.
ABSTRACT This study investigates sulfur spillover, the spontaneous and rapid spread of sulfur over carbon surfaces at ambient temperature. The process is studied by small‐angle X‐ray scattering (SAXS), X‐ray radiography, and microcalorimetry from which a number of physicochemical properties are derived.
Francesco Piccolo, Anka Berger, Sebastian Risse, Román Healy Corominas, Wilhelm Erth, Florian Fuchs, Jesus Andrade, Jörg Schuster, Marc Armbrüster, Philipp Adelhelm   +9 more
wiley   +1 more source

Mevinphos: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Carbaryl: MAK Value Documentation, addendum - Translation of the German version from 2024. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

Aufbau und Aufgaben der Deutschen Forschungsgemeinschaft

, 1975
Deutsche Forschungsgemeinschaft
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