Results 101 to 110 of about 953,705 (390)
The impact of European integration on the German system of pharmaceutical product authorization [PDF]
, 2008 The European Union has evolved since 1965 into an influential political player in the regulation of pharmaceutical safety standards. The objective of establishing a single European market for pharmaceuticals makes it necessary for member-states to adopt ...
Schmucker, Rolf
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Hartz IV – Welfare to Work in Germany [PDF]
Workfare, Wohlfahrtstheorie, Arbeitslosigkeit, Arbeitslosenversicherung, Deutschland, Welfare economics, Unemployment, Unemployment insurance ...
Wolfgang Ochel
core
The Assessment Of Geographical Borders In Economic Research [PDF]
, 2016 The length of common border between two geographical units is frequently used as a basic weight in spatial analysis. The newest methodological propositions such as tests for hierarchical relations (Markowska et. al. 2014; Sokołowski et. al.
Markowska, Małgorzata +1 more
core +2 more sources
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
„Rücken“ kostet pro Jahr 11,6 Milliarden Euro
Monitor VersorgungsforschungMit den seit 2019 jährlich erscheinenden Gesundheitsatlas-Ausgaben des Wissenschaftlichen Instituts der AOK (WIdO) wird die Gesundheitssituation aller Einwohner:innen in den 400 Landkreisen und Städten Deutschlands transparent gemacht.
Peter Stegmaier
doaj +1 more source
The empirical relevance of minimum wages for the low-wage sector [PDF]
Niedriglohn, Mindestlohn, Wirtschaftlichkeit, Arbeitsplatz, Deutschland, Low wages, Minimum wage, Economic effectiveness, Job ...
Joachim Ragnitz, Marcel Thum
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
GMS Medizinische Informatik, Biometrie und EpidemiologieUm der Vielzahl an Herausforderungen des Gesundheitswesens im 21. Jahrhundert zu begegnen, greifen immer mehr Krankenhäuser auf digitale Dokumentationssysteme zurück.
Schießer, Sophia +2 more
doaj +1 more source