Results 211 to 220 of about 465,241 (309)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

[Care for uncontrolled asthma in Germany - with focus on Magdeburg and Mannheim regions]. [PDF]

open access: yesDtsch Med Wochenschr
Herth F   +4 more
europepmc   +1 more source

Zeyttungen der Schlaraffenreyche in Deutschland und Österreich ofizielles Organ der Landesverbände Deutschland und Österreich

open access: yes, 1957
Schlaraffenrat der Schlaraffenreyche in Deutschland   +1 more
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Cardiac Arrest as an Extended Indication for Organ Donation: An Analysis of Potential in Germany Based on Retrospective Data From European Countries. [PDF]

open access: yesDtsch Arztebl Int
von Samson-Himmelstjerna FA   +13 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

[Position paper on prehabilitation in Germany]. [PDF]

open access: yesChirurgie (Heidelb)
Wobith M   +5 more
europepmc   +1 more source

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