Results 71 to 80 of about 529,072 (298)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Flexibilisierung von Kälteversorgungssystemen für den elektrischen Energieausgleich in Deutschland
, 2023 Flexibilisierung von Kälteversorgungssystemen für den elektrischen Energieausgleich in Deutschland Zuwendungsempfänger Fraunhofer-Gesellschaft zur Förderung der angew andten Forschung e ...
Khorsandnejad, Ehsan +3 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
RUDN Journal of Public Administration, 2016 Im Artikel wird wenig besprochenes in deutscher wissenschaftlicher Literatur Problem der Verbindung zwischen Arbeitslosigkeit und der sozialen Aktivitt der Bundesbrger betrachtet.
Evgenia E Koppel, Galina I Bykova
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
, 1996 Krause-Girth, C.: Aktuelles aus Deutschland: Der Kampf ums Psychotherapeutengesetz und noch ein DachverbandDie Deutsche Gesellschaft für Verhaltenstherapie (DGVT) stellt sich vorKammer, D.: Zum aktuellen Stand der Diskussion um das deutsche ...
Forum Deutschland, Redaktion
core
Deutschland gehört im Quantencomputing wissenschaftlich zur Weltspitze, droht aber bei der industriellen Anwendung den Anschluss zu verlieren. Das im Projekt »Q.E.D.« entstandene Whitepaper des Fraunhofer ISI analysiert die deutsche Quantencomputing ...
Molina Vogelsang, Manuel +8 more
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, 2012 Zentrale Ergebnisse der beiden Studien „Angebote und Strukturen der islamischen Organisationen in Deutschland“ sowie „Islamische Religionsbedienstete in Deutschland“
Stichs, Anja +3 more
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